"Insulin Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
Descriptor ID |
D007333
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MeSH Number(s) |
C18.452.394.968.500 G07.690.773.984.617
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin Resistance".
Below are MeSH descriptors whose meaning is more specific than "Insulin Resistance".
This graph shows the total number of publications written about "Insulin Resistance" by people in this website by year, and whether "Insulin Resistance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
2000 | 1 | 1 | 2 |
2002 | 2 | 4 | 6 |
2003 | 3 | 0 | 3 |
2004 | 3 | 1 | 4 |
2005 | 2 | 1 | 3 |
2006 | 1 | 2 | 3 |
2007 | 2 | 4 | 6 |
2008 | 2 | 3 | 5 |
2009 | 2 | 2 | 4 |
2010 | 4 | 2 | 6 |
2011 | 1 | 2 | 3 |
2012 | 4 | 4 | 8 |
2013 | 5 | 1 | 6 |
2014 | 3 | 3 | 6 |
2015 | 2 | 6 | 8 |
2016 | 2 | 6 | 8 |
2017 | 3 | 4 | 7 |
2018 | 2 | 3 | 5 |
2019 | 3 | 2 | 5 |
2020 | 0 | 3 | 3 |
2021 | 5 | 3 | 8 |
2022 | 6 | 0 | 6 |
2023 | 4 | 0 | 4 |
2024 | 4 | 3 | 7 |
2025 | 1 | 3 | 4 |
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Below are the most recent publications written about "Insulin Resistance" by people in Profiles.
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Youth-onset type 2 diabetes: Advances, treatments, and challenges in prevention. J Clin Lipidol. 2025 Sep-Oct; 19(4S):29-36.
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Novel Function for Endothelial Protease-Activated Receptors in Modulating Insulin Receptor Activity With Implications for Diabetes. Arterioscler Thromb Vasc Biol. 2025 Sep; 45(9):1648-1663.
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Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model. Nutrients. 2025 May 15; 17(10).
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Targeting IRE1a improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice. Elife. 2025 Apr 17; 13.
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PFKFB3 protein in adipose tissue contributes to whole body glucose homeostasis. FASEB J. 2024 Dec 15; 38(23):e70254.
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Sexually dimorphic metabolic effects of a high fat diet on knee osteoarthritis in mice. Biol Sex Differ. 2024 Dec 05; 15(1):103.
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Short-term high-calorie high-fat feeding induces hyperinsulinemia and blunts skeletal muscle microvascular blood flow in healthy humans. Am J Physiol Endocrinol Metab. 2024 Jul 01; 327(1):E42-E54.
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Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance. Proc Natl Acad Sci U S A. 2024 Apr 23; 121(17):e2320934121.
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Role of human Kallistatin in glucose and energy homeostasis in mice. Mol Metab. 2024 Apr; 82:101905.
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Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High-Fat, High-Fructose, High-Cholesterol Diet Mouse Model. Int J Mol Sci. 2024 Feb 28; 25(5).