"Homocysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiol-containing amino acid formed by a demethylation of METHIONINE.
| Descriptor ID |
D006710
|
| MeSH Number(s) |
D02.886.030.498 D12.125.166.498
|
| Concept/Terms |
Homocysteine- Homocysteine
- 2-amino-4-mercaptobutyric acid
- 2 amino 4 mercaptobutyric acid
- Homocysteine, L-Isomer
- Homocysteine, L Isomer
- L-Isomer Homocysteine
|
Below are MeSH descriptors whose meaning is more general than "Homocysteine".
Below are MeSH descriptors whose meaning is more specific than "Homocysteine".
This graph shows the total number of publications written about "Homocysteine" by people in this website by year, and whether "Homocysteine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2005 | 4 | 2 | 6 |
| 2006 | 4 | 3 | 7 |
| 2007 | 3 | 1 | 4 |
| 2008 | 4 | 2 | 6 |
| 2009 | 0 | 2 | 2 |
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Below are the most recent publications written about "Homocysteine" by people in Profiles.
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Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues. J Am Chem Soc. 2009 Jan 28; 131(3):1243-50.
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H2S protects against methionine-induced oxidative stress in brain endothelial cells. Antioxid Redox Signal. 2009 Jan; 11(1):25-33.
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Homocysteine effects classical pathway of GPCR down regulation: Galpha(q/11), Galpha(12/13), G(i/o). Mol Cell Biochem. 2009 Jan; 321(1-2):1-8.
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Homocysteine decreases blood flow to the brain due to vascular resistance in carotid artery. Neurochem Int. 2008 Dec; 53(6-8):214-9.
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Cytochrome P450 (CYP) 2J2 gene transfection attenuates MMP-9 via inhibition of NF-kappabeta in hyperhomocysteinemia. J Cell Physiol. 2008 Jun; 215(3):771-81.
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GABAA receptor agonist mitigates homocysteine-induced cerebrovascular remodeling in knockout mice. Brain Res. 2008 Jul 24; 1221:147-53.
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Mitochondrial MMP activation, dysfunction and arrhythmogenesis in hyperhomocysteinemia. Curr Vasc Pharmacol. 2008 Apr; 6(2):84-92.
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Role of copper and homocysteine in pressure overload heart failure. Cardiovasc Toxicol. 2008; 8(3):137-44.
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gamma-Aminbuturic acid A receptor mitigates homocysteine-induced endothelial cell permeability. Endothelium. 2007 Nov-Dec; 14(6):315-23.
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Cystathionine-beta-synthase gene transfer and 3-deazaadenosine ameliorate inflammatory response in endothelial cells. Am J Physiol Cell Physiol. 2007 Dec; 293(6):C1779-87.