"Off-Label Use" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
| Descriptor ID |
D056687
|
| MeSH Number(s) |
E02.319.307.500
|
| Concept/Terms |
Off-Label Use- Off-Label Use
- Off Label Use
- Off-Label Uses
- Use, Off-Label
- Uses, Off-Label
- Off-Label Prescribing
- Off Label Prescribing
- Off-Label Prescribings
- Prescribing, Off-Label
- Prescribings, Off-Label
- Unlabeled Indication
- Indication, Unlabeled
- Indications, Unlabeled
- Unlabeled Indications
|
Below are MeSH descriptors whose meaning is more general than "Off-Label Use".
Below are MeSH descriptors whose meaning is more specific than "Off-Label Use".
This graph shows the total number of publications written about "Off-Label Use" by people in this website by year, and whether "Off-Label Use" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 |
| 2015 | 1 | 1 | 2 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Off-Label Use" by people in Profiles.
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Efficacy and safety of low dose rivaroxaban in patients with coronary heart disease: a systematic review and meta-analysis. J Thromb Thrombolysis. 2020 Nov; 50(4):913-920.
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Use of Direct Oral Anticoagulants in the Treatment of Left Ventricular Thrombi: A Systematic Review. Am J Med. 2020 11; 133(11):1266-1273.e6.
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Thromboelastography-targeted management of severe coagulopathy and off-label use of four-factor prothrombin complex concentrate in an infant with massive bleeding. Blood Coagul Fibrinolysis. 2020 Mar; 31(2):170-173.
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Survey of the Effectiveness of Internet Information on Patient Education for Bone Morphogenetic Protein. World Neurosurg. 2016 Mar; 87:613-8.
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On-label and off-label drug use in the treatment of endometriosis. Fertil Steril. 2015 Mar; 103(3):612-25.
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The role of the U.S. Food and Drug Administration in device evaluation and monitoring. Gastrointest Endosc. 2010 Jul; 72(1):5-10.
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Symptomatic ectopic bone formation after off-label use of recombinant human bone morphogenetic protein-2 in transforaminal lumbar interbody fusion. J Neurosurg Spine. 2010 Jan; 12(1):40-6.