Receptors, Adrenomedullin
"Receptors, Adrenomedullin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
G-protein-coupled cell surface receptors for ADRENOMEDULLIN. They are formed by the heterodimerization of CALCITONIN RECEPTOR-LIKE PROTEIN and either RECEPTOR ACTIVITY-MODIFYING PROTEIN 2 or RECEPTOR ACTIVITY-MODIFYING PROTEIN 3.
| Descriptor ID |
D058265
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| MeSH Number(s) |
D12.776.543.750.695.041 D12.776.543.750.750.049
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenomedullin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenomedullin".
This graph shows the total number of publications written about "Receptors, Adrenomedullin" by people in this website by year, and whether "Receptors, Adrenomedullin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Adrenomedullin" by people in Profiles.
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Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin2 G protein-coupled receptor. J Biol Chem. 2023 06; 299(6):104785.
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Biochemical characterization of G protein coupling to calcitonin gene-related peptide and adrenomedullin receptors using a native PAGE assay. J Biol Chem. 2020 07 10; 295(28):9736-9751.
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Structure-function analyses reveal a triple ß-turn receptor-bound conformation of adrenomedullin 2/intermedin and enable peptide antagonist design. J Biol Chem. 2018 10 12; 293(41):15840-15854.
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Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties. J Biol Chem. 2016 May 27; 291(22):11657-75.
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Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins. Protein Sci. 2013 Dec; 22(12):1775-85.
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Bacterial expression and purification of a heterodimeric adrenomedullin receptor extracellular domain complex using DsbC-assisted disulfide shuffling. Protein Expr Purif. 2013 Mar; 88(1):107-13.