"cis-trans-Isomerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Enzymes that catalyze the rearrangement of geometry about double bonds. EC 5.2.
    
			
			
				
				
					
						| Descriptor ID | D019745 | 
					
						| MeSH Number(s) | D08.811.399.325 | 
					
						| Concept/Terms | cis-trans-Isomerasescis-trans-Isomerasescis trans IsomerasesIsomerases, cis-transIsomerases, cis transcis-trans Isomerases
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				Below are MeSH descriptors whose meaning is more general than "cis-trans-Isomerases".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "cis-trans-Isomerases".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "cis-trans-Isomerases" by people in this website by year, and whether "cis-trans-Isomerases" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
click here. 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2009 | 0 | 2 | 2 | 
| 2010 | 0 | 1 | 1 | 
| 2011 | 2 | 0 | 2 | 
| 2012 | 0 | 1 | 1 | 
| 2013 | 2 | 0 | 2 | 
| 2014 | 2 | 1 | 3 | 
| 2015 | 0 | 1 | 1 | 
| 2017 | 0 | 1 | 1 | 
| 2018 | 1 | 1 | 2 | 
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				Below are the most recent publications written about "cis-trans-Isomerases" by people in Profiles.
						
					
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								The interplay of environmental luminance and genetics in the retinal dystrophy induced by the dominant RPE65 mutation. Proc Natl Acad Sci U S A. 2022 03 15; 119(11):e2115202119. 
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								A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration. Biochim Biophys Acta Mol Basis Dis. 2018 Jul; 1864(7):2420-2429. 
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								Nanoparticles as Delivery Vehicles for the Treatment of Retinal Degenerative Diseases. Adv Exp Med Biol. 2018; 1074:117-123. 
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								Overexpression of Type 3 Iodothyronine Deiodinase Reduces Cone Death in the Leber Congenital Amaurosis Model Mice. Adv Exp Med Biol. 2018; 1074:125-131. 
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								Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration. FASEB J. 2017 08; 31(8):3425-3438. 
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								A Dominant Mutation in Rpe65, D477G, Delays Dark Adaptation and Disturbs the Visual Cycle in the Mutant Knock-In Mice. Am J Pathol. 2017 Mar; 187(3):517-527. 
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								PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage. PLoS One. 2015; 10(12):e0145305. 
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								Nanoparticle-assisted targeted delivery of eye-specific genes to eyes significantly improves the vision of blind mice in vivo. Nano Lett. 2014 Sep 10; 14(9):5257-63. 
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								Identification of key residues determining isomerohydrolase activity of human RPE65. J Biol Chem. 2014 Sep 26; 289(39):26743-26751. 
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								Suppressing thyroid hormone signaling preserves cone photoreceptors in mouse models of retinal degeneration. Proc Natl Acad Sci U S A. 2014 Mar 04; 111(9):3602-7.