"RNA, Catalytic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA that has catalytic activity. The catalytic RNA sequence folds to form a complex surface that can function as an enzyme in reactions with itself and other molecules. It may function even in the absence of protein. There are numerous examples of RNA species that are acted upon by catalytic RNA, however the scope of this enzyme class is not limited to a particular type of substrate.
| Descriptor ID |
D016337
|
| MeSH Number(s) |
D08.811.797 D13.444.735.790.199
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "RNA, Catalytic".
Below are MeSH descriptors whose meaning is more specific than "RNA, Catalytic".
This graph shows the total number of publications written about "RNA, Catalytic" by people in this website by year, and whether "RNA, Catalytic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2003 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA, Catalytic" by people in Profiles.
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Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation. Adv Exp Med Biol. 2016; 854:509-15.
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Antisense makes sense in engineered regenerative medicine. Pharm Res. 2009 Feb; 26(2):263-75.
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Thermodynamic stability and structural features of the J4/5 loop in a Pneumocystis carinii group I intron. Biochemistry. 2003 Dec 09; 42(48):14184-96.
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Exploration of the transition state for tertiary structure formation between an RNA helix and a large structured RNA. J Mol Biol. 2003 May 16; 328(5):1011-26.
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A single-molecule study of RNA catalysis and folding. Science. 2000 Jun 16; 288(5473):2048-51.
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Use of duplex rigidity for stability and specificity in RNA tertiary structure. Biochemistry. 2000 May 23; 39(20):6183-9.
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Characterization of a local folding event of the Tetrahymena group I ribozyme: effects of oligonucleotide substrate length, pH, and temperature on the two substrate binding steps. Biochemistry. 1999 Oct 26; 38(43):14192-204.
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Construction and characterization of lck- and fyn-specific tRNA: ribozyme chimeras. Mol Immunol. 1994 Aug; 31(12):923-32.
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Specificity of guanylic RNases to polynucleotide substrates. Biochem Biophys Res Commun. 1991 Jun 14; 177(2):630-5.