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Gorbsky, Gary

One or more keywords matched the following items that are connected to Gorbsky, Gary

Item Type	Name
Concept	Spindle Apparatus
Academic Article	Mad2 binding by phosphorylated kinetochores links error detection and checkpoint action in mitosis.
Academic Article	Regulation of microtubule stability and mitotic progression by survivin.
Academic Article	Shugoshin 1 plays a central role in kinetochore assembly and is required for kinetochore targeting of Plk1.
Academic Article	Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpoint.
Academic Article	Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase.
Academic Article	Microtubule dynamics and the movement of chromosomes.
Academic Article	Differential expression of a phosphoepitope at the kinetochores of moving chromosomes.
Academic Article	Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity.
Academic Article	Spindle checkpoint function and cellular sensitivity to antimitotic drugs.
Academic Article	The spindle checkpoint and chromosome segregation in meiosis.
Academic Article	Protein dynamics at the kinetochore: cell cycle regulation of the metaphase to anaphase transition.
Academic Article	Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.
Academic Article	A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor.
Academic Article	Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.
Academic Article	Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis.
Academic Article	Cohesion fatigue.
Academic Article	Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells.
Academic Article	The mitotic spindle checkpoint.
Academic Article	The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.
Academic Article	PKD2 interacts and co-localizes with mDia1 to mitotic spindles of dividing cells: role of mDia1 IN PKD2 localization to mitotic spindles.
Academic Article	Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores.
Academic Article	Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
Academic Article	Multiple mechanisms of chromosome movement in vertebrate cells mediated through the Ndc80 complex and dynein/dynactin.
Academic Article	GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms.
Academic Article	CSAG1 maintains the integrity of the mitotic centrosome in cells with defective p53.
Academic Article	Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.
Academic Article	Microtubule distribution in cultured cells and intact tissues: improved immunolabeling resolution through the use of reversible embedment cytochemistry.
Academic Article	Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.
Grant	Chromosome Movement in Prometaphase
Grant	The Spindle Checkpoint as a Target for Cancer
Grant	A Cell Dynamics Microscope for Live Cell Fluorescence
Academic Article	More than two populations of microtubules comprise the dynamic mitotic spindle.

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Spindle Apparatus