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Gaffney, Patrick

One or more keywords matched the following items that are connected to Gaffney, Patrick

Item Type	Name
Concept	Carrier Proteins
Concept	Monosaccharide Transport Proteins
Concept	Vitamin D-Binding Protein
Concept	rac1 GTP-Binding Protein
Concept	Protein Binding
Concept	Matrix Attachment Region Binding Proteins
Concept	Methyl-CpG-Binding Protein 2
Concept	Immunoglobulin J Recombination Signal Sequence-Binding Protein
Concept	DNA-Binding Proteins
Academic Article	PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
Academic Article	Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
Academic Article	Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
Academic Article	An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression.
Academic Article	Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
Academic Article	Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
Academic Article	Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Academic Article	Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
Academic Article	RBPJ mutations identified in two families affected by Adams-Oliver syndrome.
Academic Article	Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
Academic Article	A20-Binding Inhibitor of NF-?B Activation 1 is a Physiologic Inhibitor of NF-?B: A Molecular Switch for Inflammation and Autoimmunity.
Academic Article	Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
Academic Article	Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.
Academic Article	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.
Academic Article	Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
Academic Article	Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Academic Article	Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network.
Academic Article	Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
Academic Article	Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase.
Academic Article	ABIN1 dysfunction as a genetic basis for lupus nephritis.
Academic Article	The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
Academic Article	Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
Academic Article	Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.
Academic Article	Human effector B lymphocytes express ARID3a and secrete interferon alpha.
Academic Article	Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Academic Article	Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits.
Academic Article	Deficiencies in the DNA Binding Protein ARID3a Alter Chromatin Structures Important for Early Human Erythropoiesis.

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Carrier Proteins