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Connection

Robert Matts to Animals

This is a "connection" page, showing publications Robert Matts has written about Animals.
Connection Strength

0.746
  1. A High-Throughput Screen for Inhibitors of the Hsp90-Chaperone Machine. Methods Mol Biol. 2018; 1709:87-96.
    View in: PubMed
    Score: 0.056
  2. Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochim Biophys Acta. 2012 Jun; 1823(6):1092-101.
    View in: PubMed
    Score: 0.038
  3. Assays for identification of Hsp90 inhibitors and biochemical methods for discriminating their mechanism of action. Curr Top Med Chem. 2009; 9(15):1462-78.
    View in: PubMed
    Score: 0.030
  4. Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation. Cell Signal. 2005 Dec; 17(12):1477-85.
    View in: PubMed
    Score: 0.024
  5. Cdk2: a genuine protein kinase client of Hsp90 and Cdc37. Biochemistry. 2005 Nov 22; 44(46):15287-95.
    View in: PubMed
    Score: 0.024
  6. Interdomain interactions regulate the activation of the heme-regulated eIF 2 alpha kinase. Biochim Biophys Acta. 2005 Sep 15; 1725(2):174-81.
    View in: PubMed
    Score: 0.024
  7. Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation. Exp Cell Res. 2005 Jul 01; 307(1):212-23.
    View in: PubMed
    Score: 0.023
  8. Novobiocin induces a distinct conformation of Hsp90 and alters Hsp90-cochaperone-client interactions. Biochemistry. 2004 Jun 29; 43(25):8217-29.
    View in: PubMed
    Score: 0.022
  9. Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37. J Biol Chem. 2003 Oct 03; 278(40):38117-20.
    View in: PubMed
    Score: 0.021
  10. Evidence that protein phosphatase 5 functions to negatively modulate the maturation of the Hsp90-dependent heme-regulated eIF2alpha kinase. Biochemistry. 2002 May 28; 41(21):6770-9.
    View in: PubMed
    Score: 0.019
  11. The heme-regulated eukaryotic initiation factor 2alpha kinase. A potential regulatory target for control of protein synthesis by diffusible gases. J Biol Chem. 2001 May 04; 276(18):14875-83.
    View in: PubMed
    Score: 0.017
  12. Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase. J Biol Chem. 2001 Jan 05; 276(1):206-14.
    View in: PubMed
    Score: 0.017
  13. p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck. Mol Cell Biol. 2000 Sep; 20(18):6984-95.
    View in: PubMed
    Score: 0.017
  14. Dual role for Hsc70 in the biogenesis and regulation of the heme-regulated kinase of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol. 1999 Sep; 19(9):5861-71.
    View in: PubMed
    Score: 0.016
  15. Molybdate inhibits hsp90, induces structural changes in its C-terminal domain, and alters its interactions with substrates. Biochemistry. 1999 Mar 23; 38(12):3837-49.
    View in: PubMed
    Score: 0.015
  16. Development of a Cell-Based High-Throughput Screening Assay to Identify Porcine Host Defense Peptide-Inducing Compounds. J Immunol Res. 2018; 2018:5492941.
    View in: PubMed
    Score: 0.015
  17. Evidence that Hsc70 negatively modulates the activation of the heme-regulated eIF-2alpha kinase in rabbit reticulocyte lysate. Eur J Biochem. 1998 Aug 01; 255(3):552-62.
    View in: PubMed
    Score: 0.015
  18. High Throughput Screening for Natural Host Defense Peptide-Inducing Compounds as Novel Alternatives to Antibiotics. Front Cell Infect Microbiol. 2018; 8:191.
    View in: PubMed
    Score: 0.015
  19. Modular folding and evidence for phosphorylation-induced stabilization of an hsp90-dependent kinase. J Biol Chem. 1998 Apr 03; 273(14):8475-82.
    View in: PubMed
    Score: 0.014
  20. Changes in the expression of the heme-regulated eIF-2 alpha kinase and heat shock proteins in rabbit reticulocytes maturing during recovery from anemia. Exp Cell Res. 1998 Jan 10; 238(1):273-82.
    View in: PubMed
    Score: 0.014
  21. Luciferase renaturation assays of chaperones and chaperone antagonists. Methods Mol Biol. 1998; 102:129-41.
    View in: PubMed
    Score: 0.014
  22. Proteomic Profiling of Hsp90 Inhibitors. Methods Mol Biol. 2018; 1709:139-162.
    View in: PubMed
    Score: 0.014
  23. Cisplatin inhibits protein synthesis in rabbit reticulocyte lysate by causing an arrest in elongation. Arch Biochem Biophys. 1997 Aug 01; 344(1):200-7.
    View in: PubMed
    Score: 0.014
  24. The role of the 90-kDa heat-shock protein and its associated cohorts in stabilizing the heme-regulated eIF-2alpha kinase in reticulocyte lysates during heat stress. Eur J Biochem. 1997 Jun 01; 246(2):461-70.
    View in: PubMed
    Score: 0.014
  25. Hsp90 is obligatory for the heme-regulated eIF-2alpha kinase to acquire and maintain an activable conformation. J Biol Chem. 1997 Apr 25; 272(17):11648-56.
    View in: PubMed
    Score: 0.013
  26. Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate. Biochemistry. 1996 Oct 15; 35(41):13443-50.
    View in: PubMed
    Score: 0.013
  27. Hsp90-mediated folding of the lymphoid cell kinase p56lck. Biochemistry. 1996 Oct 15; 35(41):13451-9.
    View in: PubMed
    Score: 0.013
  28. Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human. Biochim Biophys Acta. 1996 Jul 17; 1307(3):309-17.
    View in: PubMed
    Score: 0.013
  29. Effect of interferon on protein translation during growth stages of 3T3 cells. Arch Biochem Biophys. 1996 Feb 15; 326(2):290-7.
    View in: PubMed
    Score: 0.012
  30. ATP-dependent chaperoning activity of reticulocyte lysate. J Biol Chem. 1994 Apr 01; 269(13):9493-9.
    View in: PubMed
    Score: 0.011
  31. Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors. Assay Drug Dev Technol. 2013 Oct; 11(8):478-88.
    View in: PubMed
    Score: 0.011
  32. Denatured proteins inhibit translation in hemin-supplemented rabbit reticulocyte lysate by inducing the activation of the heme-regulated eIF-2 alpha kinase. Biochemistry. 1993 Jul 27; 32(29):7323-8.
    View in: PubMed
    Score: 0.010
  33. Interactions of the heme-regulated eIF-2 alpha kinase with heat shock proteins in rabbit reticulocyte lysates. J Biol Chem. 1992 Sep 05; 267(25):18160-7.
    View in: PubMed
    Score: 0.010
  34. The relationship between protein synthesis and heat shock proteins levels in rabbit reticulocyte lysates. J Biol Chem. 1992 Sep 05; 267(25):18168-74.
    View in: PubMed
    Score: 0.010
  35. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine. Mol Cell. 2012 Aug 10; 47(3):434-43.
    View in: PubMed
    Score: 0.010
  36. Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells. BMC Cancer. 2011 Oct 31; 11:468.
    View in: PubMed
    Score: 0.009
  37. Toxic heavy metal ions activate the heme-regulated eukaryotic initiation factor-2 alpha kinase by inhibiting the capacity of hemin-supplemented reticulocyte lysates to reduce disulfide bonds. J Biol Chem. 1991 Jul 05; 266(19):12695-702.
    View in: PubMed
    Score: 0.009
  38. Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells. Prostate. 2010 Jan 01; 70(1):27-36.
    View in: PubMed
    Score: 0.008
  39. Evidence for the association of the heme-regulated eIF-2 alpha kinase with the 90-kDa heat shock protein in rabbit reticulocyte lysate in situ. J Biol Chem. 1989 Sep 15; 264(26):15542-7.
    View in: PubMed
    Score: 0.008
  40. Correlation between the distribution of the reversing factor and eukaryotic initiation factor 2 in heme-deficient or double-stranded RNA-inhibited reticulocyte lysates. FEBS Lett. 1988 Aug 15; 236(1):179-84.
    View in: PubMed
    Score: 0.007
  41. Inhibition of rabbit reticulocyte lysate protein synthesis by heavy metal ions involves the phosphorylation of the alpha-subunit of the eukaryotic initiation factor 2. J Biol Chem. 1987 Nov 25; 262(33):15939-45.
    View in: PubMed
    Score: 0.007
  42. Derrubone, an inhibitor of the Hsp90 protein folding machinery. J Nat Prod. 2007 Dec; 70(12):2014-8.
    View in: PubMed
    Score: 0.007
  43. Phosphorothioated binary complex of eukaryotic initiation factor eIF-2 and GDP inhibits protein synthesis in hemin-supplemented reticulocyte lysates. Biochem Biophys Res Commun. 1987 Sep 15; 147(2):772-7.
    View in: PubMed
    Score: 0.007
  44. Fate of reversing factor during restoration of protein synthesis by hemin or GTP in heme-deficient reticulocyte lysates. Proc Natl Acad Sci U S A. 1986 Mar; 83(5):1217-21.
    View in: PubMed
    Score: 0.006
  45. Direct ribosomal binding by a cellular inhibitor of translation. Nat Struct Mol Biol. 2006 Feb; 13(2):103-11.
    View in: PubMed
    Score: 0.006
  46. Direct interaction of the cell division cycle 37 homolog inhibits endothelial nitric oxide synthase activity. Circ Res. 2006 Feb 17; 98(3):335-41.
    View in: PubMed
    Score: 0.006
  47. The regulation of initiation of protein synthesis by phosphorylation of eIF-2(alpha) and the role of reversing factor in the recycling of eIF-2. J Biol Chem. 1984 Jun 10; 259(11):6708-11.
    View in: PubMed
    Score: 0.006
  48. Identification of crucial histidines for heme binding in the N-terminal domain of the heme-regulated eIF2alpha kinase. J Biol Chem. 2004 Feb 20; 279(8):6778-82.
    View in: PubMed
    Score: 0.005
  49. Effect of phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 on the function of reversing factor in the initiation of protein synthesis. Proc Natl Acad Sci U S A. 1983 May; 80(9):2559-63.
    View in: PubMed
    Score: 0.005
  50. The molecular chaperone Hsp90 is required for signal transduction by wild-type Hck and maintenance of its constitutively active counterpart. Cell Growth Differ. 2001 Aug; 12(8):409-17.
    View in: PubMed
    Score: 0.005
  51. Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases. J Immunol. 2000 Mar 15; 164(6):2915-23.
    View in: PubMed
    Score: 0.004
  52. The N-terminal region of the heme-regulated eIF2alpha kinase is an autonomous heme binding domain. Eur J Biochem. 2000 Jan; 267(2):498-506.
    View in: PubMed
    Score: 0.004
  53. Regulation of hepatic poly(A) endonuclease by corticosterone and amino acids. J Biol Chem. 1979 Nov 25; 254(22):11228-33.
    View in: PubMed
    Score: 0.004
  54. Disruption of zebrafish somite development by pharmacologic inhibition of Hsp90. Dev Biol. 1999 Jun 01; 210(1):56-70.
    View in: PubMed
    Score: 0.004
  55. Cloning and characterization of complementary and genomic DNAs encoding the epsilon-subunit of rat translation initiation factor-2B. Biochim Biophys Acta. 1996 Jul 17; 1307(3):318-24.
    View in: PubMed
    Score: 0.003
  56. Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae. Mol Cell Biol. 1993 Mar; 13(3):1920-32.
    View in: PubMed
    Score: 0.003
  57. The storage of globin mRNA during the inhibition of protein synthesis by heme deprivation. Biochem Biophys Res Commun. 1986 Feb 13; 134(3):1048-55.
    View in: PubMed
    Score: 0.002
  58. Distribution of reversing factor in reticulocyte lysates during active protein synthesis and on inhibition by heme deprivation or double-stranded RNA. Proc Natl Acad Sci U S A. 1984 Nov; 81(22):6998-7002.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

THIS IS A DEVELOPMENT VERSION OF PROFILES. PLEASE GO TO THE PRODUCTION ENVIRONMENT FOR UPDATES