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Connection

Raju Rajala to Animals

This is a "connection" page, showing publications Raju Rajala has written about Animals.
Connection Strength

2.698
  1. Girdin: A Class I Phosphatidylinositol 3-Kinase-Binding Protein in the Retina. Adv Exp Med Biol. 2025; 1468:299-303.
    View in: PubMed
    Score: 0.091
  2. Phosphoinositide 3-Kinase Enhancer Protein: Insights into Its Expression and Functions in Retinal Cells. Adv Exp Med Biol. 2025; 1468:417-421.
    View in: PubMed
    Score: 0.091
  3. Age-related retinal degeneration resulting from the deletion of Shp2 tyrosine phosphatase in photoreceptor neurons. Cell Death Dis. 2024 Aug 08; 15(8):577.
    View in: PubMed
    Score: 0.088
  4. Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection. Cell Death Dis. 2022 Jul 15; 13(7):613.
    View in: PubMed
    Score: 0.077
  5. Ribosomal targeting strategy and nuclear labeling to analyze photoreceptor phosphoinositide signatures. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 08; 1867(8):159161.
    View in: PubMed
    Score: 0.075
  6. Regulation of Phosphoinositide Levels in the Retina by Protein Tyrosine Phosphatase 1B and Growth Factor Receptor-Bound Protein 14. Biomolecules. 2021 04 19; 11(4).
    View in: PubMed
    Score: 0.070
  7. Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy. Sci Rep. 2020 05 04; 10(1):7456.
    View in: PubMed
    Score: 0.066
  8. A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons. Cell Biol Int. 2020 Apr; 44(4):1020-1027.
    View in: PubMed
    Score: 0.064
  9. Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration. Cell Death Dis. 2018 07 03; 9(7):737.
    View in: PubMed
    Score: 0.058
  10. Pyruvate kinase M2 regulates photoreceptor structure, function, and viability. Cell Death Dis. 2018 02 14; 9(2):240.
    View in: PubMed
    Score: 0.056
  11. Nanoparticles as Delivery Vehicles for the Treatment of Retinal Degenerative Diseases. Adv Exp Med Biol. 2018; 1074:117-123.
    View in: PubMed
    Score: 0.056
  12. Constitutive Activation Mutant mTOR Promote Cone Survival in Retinitis Pigmentosa Mice. Adv Exp Med Biol. 2018; 1074:491-497.
    View in: PubMed
    Score: 0.056
  13. Redundant and Nonredundant Functions of Akt Isoforms in the Retina. Adv Exp Med Biol. 2018; 1074:585-591.
    View in: PubMed
    Score: 0.056
  14. The Warburg Effect Mediator Pyruvate Kinase M2 Expression and Regulation in the Retina. Sci Rep. 2016 11 24; 6:37727.
    View in: PubMed
    Score: 0.052
  15. Activation of oncogenic tyrosine kinase signaling promotes insulin receptor-mediated cone photoreceptor survival. Oncotarget. 2016 Jul 26; 7(30):46924-46942.
    View in: PubMed
    Score: 0.051
  16. Cell-Specific Promoters Enable Lipid-Based Nanoparticles to Deliver Genes to Specific Cells of the Retina In Vivo. Theranostics. 2016; 6(10):1514-27.
    View in: PubMed
    Score: 0.050
  17. Class I Phosphoinositide 3-Kinase Exerts a Differential Role on Cell Survival and Cell Trafficking in Retina. Adv Exp Med Biol. 2016; 854:363-9.
    View in: PubMed
    Score: 0.049
  18. The p110a isoform of phosphoinositide 3-kinase is essential for cone photoreceptor survival. Biochimie. 2015 May; 112:35-40.
    View in: PubMed
    Score: 0.046
  19. Non-canonical regulation of phosphatidylinositol 3-kinase gamma isoform activity in retinal rod photoreceptor cells. Cell Commun Signal. 2015 Feb 03; 13:7.
    View in: PubMed
    Score: 0.046
  20. Effect of knocking down the insulin receptor on mouse rod responses. Sci Rep. 2015 Jan 19; 5:7858.
    View in: PubMed
    Score: 0.046
  21. Nanoparticle-assisted targeted delivery of eye-specific genes to eyes significantly improves the vision of blind mice in vivo. Nano Lett. 2014 Sep 10; 14(9):5257-63.
    View in: PubMed
    Score: 0.044
  22. Phosphoinositides: minor lipids make a major impact on photoreceptor cell functions. Sci Rep. 2014 Jun 26; 4:5463.
    View in: PubMed
    Score: 0.044
  23. Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation. Cell Commun Signal. 2013 Dec 18; 11:96.
    View in: PubMed
    Score: 0.042
  24. Neuroprotective role of protein tyrosine phosphatase-1B in rod photoreceptor neurons. Protein Cell. 2013 Dec; 4(12):890-2.
    View in: PubMed
    Score: 0.042
  25. Modulation of mouse rod photoreceptor responses by Grb14 protein. J Biol Chem. 2014 Jan 03; 289(1):358-64.
    View in: PubMed
    Score: 0.042
  26. Light activation of the insulin receptor regulates mitochondrial hexokinase. A possible mechanism of retinal neuroprotection. Mitochondrion. 2013 Nov; 13(6):566-76.
    View in: PubMed
    Score: 0.041
  27. Insulin receptor signaling in cones. J Biol Chem. 2013 Jul 05; 288(27):19503-15.
    View in: PubMed
    Score: 0.041
  28. Insulin receptor regulates photoreceptor CNG channel activity. Am J Physiol Endocrinol Metab. 2012 Dec 01; 303(11):E1363-72.
    View in: PubMed
    Score: 0.039
  29. Conservation and divergence of Grb7 family of Ras-binding domains. Protein Cell. 2012 Jan; 3(1):60-70.
    View in: PubMed
    Score: 0.037
  30. Protein tyrosine phosphatase 1B: a novel molecular target for retinal degenerative diseases. Adv Exp Med Biol. 2012; 723:829-34.
    View in: PubMed
    Score: 0.037
  31. Mechanism involved in the modulation of photoreceptor-specific cyclic nucleotidegated channel by the tyrosine kinase adapter protein Grb14. Protein Cell. 2011 Nov; 2(11):906-17.
    View in: PubMed
    Score: 0.037
  32. Phosphoinositide 3-kinase signaling in retinal rod photoreceptors. Invest Ophthalmol Vis Sci. 2011 Aug 11; 52(9):6355-62.
    View in: PubMed
    Score: 0.036
  33. Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14. Mol Cell Biol. 2011 Oct; 31(19):3975-87.
    View in: PubMed
    Score: 0.036
  34. Deletion of the p85alpha regulatory subunit of phosphoinositide 3-kinase in cone photoreceptor cells results in cone photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2011 Jun 01; 52(6):3775-83.
    View in: PubMed
    Score: 0.035
  35. Growth factor receptor-bound protein 14: a new modulator of photoreceptor-specific cyclic-nucleotide-gated channel. EMBO Rep. 2010 Nov; 11(11):861-7.
    View in: PubMed
    Score: 0.034
  36. Focus on molecules: phosphatidylinositol-4,5-bisphosphate (PIP2). Exp Eye Res. 2010 Sep; 91(3):324-5.
    View in: PubMed
    Score: 0.033
  37. Rhodopsin-regulated insulin receptor signaling pathway in rod photoreceptor neurons. Mol Neurobiol. 2010 Aug; 42(1):39-47.
    View in: PubMed
    Score: 0.033
  38. Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II a phosphatidylinositol-5-phosphate 4-kinase. Neurochem Res. 2011 Apr; 36(4):627-35.
    View in: PubMed
    Score: 0.033
  39. Serine/threonine kinase akt activation regulates the activity of retinal serine/threonine phosphatases, PHLPP and PHLPPL. J Neurochem. 2010 Apr; 113(2):477-88.
    View in: PubMed
    Score: 0.032
  40. Enhanced retinal insulin receptor-activated neuroprotective survival signal in mice lacking the protein-tyrosine phosphatase-1B gene. J Biol Chem. 2010 Mar 19; 285(12):8894-904.
    View in: PubMed
    Score: 0.032
  41. Phosphoinositide 3-kinase signaling in the vertebrate retina. J Lipid Res. 2010 Jan; 51(1):4-22.
    View in: PubMed
    Score: 0.032
  42. Insulin receptor signaling regulates actin cytoskeletal organization in developing photoreceptors. J Neurochem. 2009 Sep; 110(5):1648-60.
    View in: PubMed
    Score: 0.031
  43. Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation. Biochemistry. 2009 Jun 23; 48(24):5563-72.
    View in: PubMed
    Score: 0.031
  44. Cytoskeletal components enhance the autophosphorylation of retinal insulin receptor. Chem Biol Interact. 2009 Jul 15; 180(2):245-53.
    View in: PubMed
    Score: 0.031
  45. Retinal insulin receptor signaling in hyperosmotic stress. Vitam Horm. 2009; 80:583-612.
    View in: PubMed
    Score: 0.030
  46. Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity. Invest Ophthalmol Vis Sci. 2009 Mar; 50(3):1033-40.
    View in: PubMed
    Score: 0.030
  47. Activation and membrane binding of retinal protein kinase Balpha/Akt1 is regulated through light-dependent generation of phosphoinositides. J Neurochem. 2008 Dec; 107(5):1382-97.
    View in: PubMed
    Score: 0.029
  48. Insulin growth factor 1 receptor/PI3K/AKT survival pathway in outer segment membranes of rod photoreceptors. Invest Ophthalmol Vis Sci. 2008 Nov; 49(11):4765-73.
    View in: PubMed
    Score: 0.029
  49. Loss of neuroprotective survival signal in mice lacking insulin receptor gene in rod photoreceptor cells. J Biol Chem. 2008 Jul 11; 283(28):19781-92.
    View in: PubMed
    Score: 0.029
  50. G-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptor. J Biol Chem. 2007 Mar 30; 282(13):9865-9873.
    View in: PubMed
    Score: 0.026
  51. Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death. J Neurosci. 2007 Jan 03; 27(1):203-11.
    View in: PubMed
    Score: 0.026
  52. Localization of the insulin receptor and phosphoinositide 3-kinase in detergent-resistant membrane rafts of rod photoreceptor outer segments. Adv Exp Med Biol. 2006; 572:491-7.
    View in: PubMed
    Score: 0.024
  53. Lipid-protein interactions of growth factor receptor-bound protein 14 in insulin receptor signaling. Biochemistry. 2005 Nov 29; 44(47):15461-71.
    View in: PubMed
    Score: 0.024
  54. Identification of a NPXY motif in growth factor receptor-bound protein 14 (Grb14) and its interaction with the phosphotyrosine-binding (PTB) domain of IRS-1. Biochemistry. 2005 Jun 07; 44(22):7929-35.
    View in: PubMed
    Score: 0.023
  55. Interaction of the retinal insulin receptor beta-subunit with the p85 subunit of phosphoinositide 3-kinase. Biochemistry. 2004 May 18; 43(19):5637-50.
    View in: PubMed
    Score: 0.022
  56. Light regulation of the insulin receptor in the retina. Mol Neurobiol. 2003 Oct; 28(2):123-38.
    View in: PubMed
    Score: 0.021
  57. Regulation of retinal phosphoinositide 3-kinase activity in p85alpha-subunit knockout mice. Adv Exp Med Biol. 2003; 533:369-76.
    View in: PubMed
    Score: 0.020
  58. In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor beta-subunit. J Biol Chem. 2002 Nov 08; 277(45):43319-26.
    View in: PubMed
    Score: 0.019
  59. mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice. J Biol Chem. 2022 06; 298(6):101944.
    View in: PubMed
    Score: 0.019
  60. Altered expression and localization of N-myristoyltransferase in experimentally induced rat model of ischemia-reperfusion. J Cell Biochem. 2002; 86(3):509-19.
    View in: PubMed
    Score: 0.018
  61. Interaction of the insulin receptor beta-subunit with phosphatidylinositol 3-kinase in bovine ROS. Invest Ophthalmol Vis Sci. 2001 Dec; 42(13):3110-7.
    View in: PubMed
    Score: 0.018
  62. ßA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells. Commun Biol. 2021 07 08; 4(1):850.
    View in: PubMed
    Score: 0.018
  63. Expression of N-myristoyltransferase inhibitor protein and its relationship to c-Src levels in human colon cancer cell lines. Biochem Biophys Res Commun. 2000 Jul 14; 273(3):1116-20.
    View in: PubMed
    Score: 0.017
  64. mTORC1 and mTORC2 expression in inner retinal neurons and glial cells. Exp Eye Res. 2020 08; 197:108131.
    View in: PubMed
    Score: 0.017
  65. N-myristoyltransferase. Mol Cell Biochem. 2000 Jan; 204(1-2):135-55.
    View in: PubMed
    Score: 0.016
  66. Pathogenic Role of microRNA-21 in Diabetic Retinopathy Through Downregulation of PPARa. Diabetes. 2017 06; 66(6):1671-1682.
    View in: PubMed
    Score: 0.013
  67. Loss of human disease protein retinitis pigmentosa GTPase regulator (RPGR) differentially affects rod or cone-enriched retina. Hum Mol Genet. 2016 Apr 01; 25(7):1345-56.
    View in: PubMed
    Score: 0.012
  68. MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization. FEBS Lett. 2015 Apr 28; 589(10):1143-1149.
    View in: PubMed
    Score: 0.012
  69. Myristoyl CoA:protein N-myristoyltransferase: subcellular localization, activation and kinetic behavior in the presence of organic solvents. Biochem Biophys Res Commun. 1995 Mar 17; 208(2):617-23.
    View in: PubMed
    Score: 0.012
  70. Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads to leber congenital amaurosis-1. J Biol Chem. 2015 Feb 06; 290(6):3488-99.
    View in: PubMed
    Score: 0.011
  71. Molecular characterization of a gene encoding N-myristoyl transferase (NMT) from Triticum aestivum (bread wheat). Genome. 2004 Dec; 47(6):1036-42.
    View in: PubMed
    Score: 0.006
  72. Myristoyl-CoA:protein N-myristoyltransferases: isoform identification and gene expression in retina. Mol Vis. 2004 Mar 22; 10:177-85.
    View in: PubMed
    Score: 0.005
  73. Involvement of insulin/phosphoinositide 3-kinase/Akt signal pathway in 17 beta-estradiol-mediated neuroprotection. J Biol Chem. 2004 Mar 26; 279(13):13086-94.
    View in: PubMed
    Score: 0.005
  74. Neuroprotective effect of estrogen upon retinal neurons in vitro. Adv Exp Med Biol. 2003; 533:395-402.
    View in: PubMed
    Score: 0.005
  75. Characterization of Type I and Type II myristoyl-CoA:protein N-myristoyltransferases with the Acyl-CoAs found on heterogeneously acylated retinal proteins. Exp Eye Res. 2002 Jul; 75(1):87-97.
    View in: PubMed
    Score: 0.005
  76. Calmodulin-dependent cyclic nucleotide phosphodiesterase in an experimental rat model of cardiac ischemia-reperfusion. Can J Physiol Pharmacol. 2002 Jan; 80(1):59-66.
    View in: PubMed
    Score: 0.005
  77. Decreased expression of high-molecular-weight calmodulin-binding protein and its correlation with apoptosis in ischemia-reperfused rat heart. Cell Calcium. 2001 Jan; 29(1):59-71.
    View in: PubMed
    Score: 0.004
  78. Altered expression of high-molecular-weight calmodulin-binding protein in human ischaemic myocardium. J Pathol. 2000 Jun; 191(2):208-16.
    View in: PubMed
    Score: 0.004
  79. Molecular cloning, genomic organization, and biochemical characterization of myristoyl-CoA:protein N-myristoyltransferase from Arabidopsis thaliana. J Biol Chem. 2000 Mar 31; 275(13):9673-83.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

THIS IS A DEVELOPMENT VERSION OF PROFILES. PLEASE GO TO THE PRODUCTION ENVIRONMENT FOR UPDATES