Anna Csiszar to Animals
This is a "connection" page, showing publications Anna Csiszar has written about Animals.
Connection Strength
3.989
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Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence. Nutrients. 2024 Mar 26; 16(7).
Score: 0.087
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Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)-induced chemobrain. Aging Cell. 2023 07; 22(7):e13832.
Score: 0.082
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Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain. Geroscience. 2022 04; 44(2):661-681.
Score: 0.075
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype. Geroscience. 2021 10; 43(5):2387-2394.
Score: 0.073
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Companion animals likely do not spread COVID-19 but may get infected themselves. Geroscience. 2020 10; 42(5):1229-1236.
Score: 0.068
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Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar. J Am Coll Cardiol. 2020 03 03; 75(8):931-941.
Score: 0.066
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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice. Geroscience. 2019 10; 41(5):609-617.
Score: 0.064
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Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability. J Gerontol A Biol Sci Med Sci. 2019 08 16; 74(9):1417-1421.
Score: 0.063
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Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227.
Score: 0.062
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Role of endothelial NAD+ deficiency in age-related vascular dysfunction. Am J Physiol Heart Circ Physiol. 2019 06 01; 316(6):H1253-H1266.
Score: 0.061
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IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454.
Score: 0.061
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Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):290-298.
Score: 0.061
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Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation. Geroscience. 2018 12; 40(5-6):513-521.
Score: 0.060
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Mechanisms of Vascular Aging. Circ Res. 2018 09 14; 123(7):849-867.
Score: 0.059
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Endothelial dysfunction and angiogenesis impairment in the ageing vasculature. Nat Rev Cardiol. 2018 09; 15(9):555-565.
Score: 0.059
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):853-863.
Score: 0.058
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Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline. Exp Gerontol. 2017 08; 94:52-58.
Score: 0.052
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Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
Score: 0.052
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IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
Score: 0.051
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Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
Score: 0.044
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Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52.
Score: 0.044
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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease. J Gerontol A Biol Sci Med Sci. 2014 Oct; 69(10):1212-26.
Score: 0.042
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Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease. Am J Physiol Heart Circ Physiol. 2013 Oct 15; 305(8):H1120-30.
Score: 0.042
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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68(8):877-91.
Score: 0.040
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Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Mar; 68(3):235-49.
Score: 0.039
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The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):599-610.
Score: 0.038
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Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):811-20.
Score: 0.037
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Testing the oxidative stress hypothesis of aging in primate fibroblasts: is there a correlation between species longevity and cellular ROS production? J Gerontol A Biol Sci Med Sci. 2012 Aug; 67(8):841-52.
Score: 0.037
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Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):313-29.
Score: 0.037
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Mitochondrial protection by resveratrol. Exerc Sport Sci Rev. 2011 Jul; 39(3):128-32.
Score: 0.036
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Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci. 2011 Aug; 66(8):866-75.
Score: 0.036
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Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H363-72.
Score: 0.036
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Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal. J Gerontol A Biol Sci Med Sci. 2011 Jul; 66(7):741-50.
Score: 0.035
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Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Akar et al. Cardiovasc Drugs Ther. 2011 Apr; 25(2):111-3.
Score: 0.035
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Free radical production, antioxidant capacity, and oxidative stress response signatures in fibroblasts from Lewis dwarf rats: effects of life span-extending peripubertal GH treatment. J Gerontol A Biol Sci Med Sci. 2011 May; 66(5):501-10.
Score: 0.035
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Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol. 2011 Apr; 300(4):H1133-40.
Score: 0.035
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Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease. Ann N Y Acad Sci. 2011 Jan; 1215:117-22.
Score: 0.035
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Vasoprotective effects of life span-extending peripubertal GH replacement in Lewis dwarf rats. J Gerontol A Biol Sci Med Sci. 2010 Nov; 65(11):1145-56.
Score: 0.034
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Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1028-41.
Score: 0.034
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Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol. 2010 Jul; 299(1):H18-24.
Score: 0.033
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Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats. Am J Physiol Heart Circ Physiol. 2010 Feb; 298(2):H346-51.
Score: 0.032
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Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats. Hypertension. 2009 Sep; 54(3):668-75.
Score: 0.031
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Hemodynamic forces, vascular oxidative stress, and regulation of BMP-2/4 expression. Antioxid Redox Signal. 2009 Jul; 11(7):1683-97.
Score: 0.031
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Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev. 2009 Aug; 130(8):518-27.
Score: 0.031
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Resveratrol induces mitochondrial biogenesis in endothelial cells. Am J Physiol Heart Circ Physiol. 2009 Jul; 297(1):H13-20.
Score: 0.031
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Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice. Am J Physiol Heart Circ Physiol. 2008 Nov; 295(5):H1882-94.
Score: 0.030
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Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H475-6.
Score: 0.029
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Inflammation and endothelial dysfunction during aging: role of NF-kappaB. J Appl Physiol (1985). 2008 Oct; 105(4):1333-41.
Score: 0.029
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Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H569-77.
Score: 0.029
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Oxidative stress in vascular senescence: lessons from successfully aging species. Front Biosci. 2008 May 01; 13:5056-70.
Score: 0.029
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Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol. 2008 Jun; 294(6):H2721-35.
Score: 0.029
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Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2121-8.
Score: 0.029
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Vascular superoxide and hydrogen peroxide production and oxidative stress resistance in two closely related rodent species with disparate longevity. Aging Cell. 2007 Dec; 6(6):783-97.
Score: 0.028
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Vascular aging in the longest-living rodent, the naked mole rat. Am J Physiol Heart Circ Physiol. 2007 Aug; 293(2):H919-27.
Score: 0.027
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Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries. Am J Physiol Heart Circ Physiol. 2007 Jul; 293(1):H37-47.
Score: 0.027
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The aging kidney: role of endothelial oxidative stress and inflammation. Acta Physiol Hung. 2007 Mar; 94(1-2):107-15.
Score: 0.027
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Downregulation of bone morphogenetic protein 4 expression in coronary arterial endothelial cells: role of shear stress and the cAMP/protein kinase A pathway. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):776-82.
Score: 0.026
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Resveratrol increases vascular oxidative stress resistance. Am J Physiol Heart Circ Physiol. 2007 May; 292(5):H2417-24.
Score: 0.026
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Vasculoprotective effects of anti-tumor necrosis factor-alpha treatment in aging. Am J Pathol. 2007 Jan; 170(1):388-98.
Score: 0.026
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Mechanosensitive production of reactive oxygen species in endothelial and smooth muscle cells: role in microvascular remodeling? Antioxid Redox Signal. 2006 Jul-Aug; 8(7-8):1121-9.
Score: 0.025
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Altered mitochondrial energy metabolism may play a role in vascular aging. Med Hypotheses. 2006; 67(4):904-8.
Score: 0.025
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Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol. 2006 Feb; 168(2):629-38.
Score: 0.025
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Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr Vasc Pharmacol. 2005 Jul; 3(3):285-91.
Score: 0.024
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Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure. Circulation. 2005 May 10; 111(18):2364-72.
Score: 0.023
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Endothelial Colony-Forming Cells (ECFCs) in cerebrovascular aging: Focus on the pathogenesis of Vascular Cognitive Impairment and Dementia (VCID), and treatment prospects. Ageing Res Rev. 2025 Feb; 104:102672.
Score: 0.023
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The effects of time restricted feeding on age-related changes in the mouse retina. Exp Gerontol. 2024 Sep; 194:112510.
Score: 0.022
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Transcriptomic signatures of time-restricted feeding (TRF) in cerebrovascular aging and cognitive health. Vascul Pharmacol. 2024 Jun; 155:107338.
Score: 0.022
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Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging. Physiol Genomics. 2004 Mar 12; 17(1):21-30.
Score: 0.022
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Synergistic effects of vascular IL-17 and TNFalpha may promote coronary artery disease. Med Hypotheses. 2004; 63(4):696-8.
Score: 0.021
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A role for the cystathionine-?-synthase /H2S axis in astrocyte dysfunction in the aging brain. Redox Biol. 2023 Dec; 68:102958.
Score: 0.021
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Tetraspanin Tspan8 restrains interferon signaling to stabilize intestinal epithelium by directing endocytosis of interferon receptor. Cell Mol Life Sci. 2023 May 19; 80(6):154.
Score: 0.020
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Aging-induced proinflammatory shift in cytokine expression profile in coronary arteries. FASEB J. 2003 Jun; 17(9):1183-5.
Score: 0.020
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Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res. 2002 Jun 14; 90(11):1159-66.
Score: 0.019
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Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981.
Score: 0.019
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Cerebral venous congestion exacerbates cerebral microhemorrhages in mice. Geroscience. 2022 04; 44(2):805-816.
Score: 0.019
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Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission. Geroscience. 2021 10; 43(5):2305-2320.
Score: 0.018
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Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice. Geroscience. 2021 10; 43(5):2427-2440.
Score: 0.018
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Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice. Geroscience. 2021 10; 43(5):2611-2619.
Score: 0.018
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Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease. Geroscience. 2021 08; 43(4):1947-1957.
Score: 0.018
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IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging. Geroscience. 2021 04; 43(2):901-911.
Score: 0.018
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Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1370-H1392.
Score: 0.017
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Obesity-induced cognitive impairment in older adults: a microvascular perspective. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H740-H761.
Score: 0.017
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Midlife Obesity Impairs Neurovascular Coupling Responses. Obesity (Silver Spring). 2021 01; 29(1):17.
Score: 0.017
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Age-related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging. Psychophysiology. 2021 07; 58(7):e13718.
Score: 0.017
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Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling. Geroscience. 2021 02; 43(1):197-212.
Score: 0.017
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Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease. Geroscience. 2020 12; 42(6):1685-1698.
Score: 0.017
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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain. Geroscience. 2020 04; 42(2):429-444.
Score: 0.016
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Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood. Geroscience. 2020 04; 42(2):727-748.
Score: 0.016
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CD82-TRPM7-Numb signaling mediates age-related cognitive impairment. Geroscience. 2020 04; 42(2):595-611.
Score: 0.016
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Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020 04; 42(2):527-546.
Score: 0.016
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Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice. Geroscience. 2020 04; 42(2):409-428.
Score: 0.016
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Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice. Geroscience. 2019 10; 41(5):575-589.
Score: 0.016
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Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. Geroscience. 2019 10; 41(5):533-542.
Score: 0.016
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Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience. 2019 12; 41(6):711-725.
Score: 0.016
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Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience. 2019 08; 41(4):419-439.
Score: 0.016
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Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 10; 41(5):619-630.
Score: 0.016
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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019 06; 24:101192.
Score: 0.015
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Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2019 05 01; 316(5):H1124-H1140.
Score: 0.015
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Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency. Neurobiol Aging. 2018 11; 71:1-12.
Score: 0.015
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Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice. Geroscience. 2018 04; 40(2):123-137.
Score: 0.014
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Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol. 2018 07; 17:47-58.
Score: 0.014
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Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. 2018 04; 17(2).
Score: 0.014
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Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2017 12; 39(5-6):601-614.
Score: 0.014
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IGF-1 has sexually dimorphic, pleiotropic, and time-dependent effects on healthspan, pathology, and lifespan. Geroscience. 2017 04; 39(2):129-145.
Score: 0.013
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Cerebral microhemorrhages: mechanisms, consequences, and prevention. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1128-H1143.
Score: 0.013
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Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.
Score: 0.013
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The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer. Geroscience. 2017 04; 39(2):147-160.
Score: 0.013
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Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence. Geroscience. 2017 02; 39(1):33-42.
Score: 0.013
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Pharmacological Strategies to Retard Cardiovascular Aging. Circ Res. 2016 05 13; 118(10):1626-42.
Score: 0.013
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Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet. Aging (Albany NY). 2016 05; 8(5):899-916.
Score: 0.013
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Biotin-conjugated fusogenic liposomes for high-quality cell purification. J Biomater Appl. 2016 Jan; 30(6):846-56.
Score: 0.012
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Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1837-45.
Score: 0.012
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IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms. J Bone Miner Res. 2016 Feb; 31(2):443-54.
Score: 0.012
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Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1871-81.
Score: 0.012
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IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. 2015 Dec; 14(6):1034-44.
Score: 0.012
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Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):527-30.
Score: 0.012
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Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell. 2015 Jun; 14(3):400-8.
Score: 0.012
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Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1355-9.
Score: 0.012
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IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97.
Score: 0.011
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Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2015 Jun; 70(6):665-74.
Score: 0.011
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Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1353-62.
Score: 0.011
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Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells. Am J Physiol Heart Circ Physiol. 2014 Sep 15; 307(6):H858-68.
Score: 0.011
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Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metab. 2014 Jul 01; 20(1):183-90.
Score: 0.011
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Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats. J Gerontol A Biol Sci Med Sci. 2015 Mar; 70(3):303-13.
Score: 0.011
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A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1448-61.
Score: 0.011
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Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. Am J Physiol Heart Circ Physiol. 2014 Feb; 306(3):H299-308.
Score: 0.011
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Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1698-708.
Score: 0.011
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Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications. J Vasc Res. 2013; 50(6):445-57.
Score: 0.011
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Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1732-42.
Score: 0.010
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Role of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics. Am J Physiol Heart Circ Physiol. 2013 Aug 15; 305(4):H459-76.
Score: 0.010
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Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: role of increased DNA damage and decreased DNA repair capacity in microvascular radiosensitivity. J Gerontol A Biol Sci Med Sci. 2013 Dec; 68(12):1443-57.
Score: 0.010
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Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats. Br J Pharmacol. 2013 Apr; 168(8):1878-88.
Score: 0.010
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Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation. J Gerontol A Biol Sci Med Sci. 2013 Jul; 68(7):780-92.
Score: 0.010
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Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):652-60.
Score: 0.010
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Resistance to genotoxic stresses in Arctica islandica, the longest living noncolonial animal: is extreme longevity associated with a multistress resistance phenotype? J Gerontol A Biol Sci Med Sci. 2013 May; 68(5):521-9.
Score: 0.010
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Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa). J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):359-67.
Score: 0.010
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Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):587-98.
Score: 0.010
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Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia. PLoS One. 2012; 7(1):e30444.
Score: 0.009
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Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):553-64.
Score: 0.009
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Bone morphogenetic protein inhibition promotes neurological recovery after intraventricular hemorrhage. J Neurosci. 2011 Aug 24; 31(34):12068-82.
Score: 0.009
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SRT1720 improves survival and healthspan of obese mice. Sci Rep. 2011; 1:70.
Score: 0.009
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Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience. 2011 Jun 30; 185:50-60.
Score: 0.009
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Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice. Am J Physiol Heart Circ Physiol. 2011 Mar; 300(3):H736-44.
Score: 0.009
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Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM. PLoS One. 2010 Jul 26; 5(7):e11800.
Score: 0.008
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Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain. Stroke. 2010 Aug; 41(8):1766-73.
Score: 0.008
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Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition. Brain. 2010 Aug; 133(Pt 8):2264-80.
Score: 0.008
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Intramyocardial VEGF-B167 gene delivery delays the progression towards congestive failure in dogs with pacing-induced dilated cardiomyopathy. Circ Res. 2010 Jun 25; 106(12):1893-903.
Score: 0.008
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Effect of hyperoxic resuscitation on propensity of germinal matrix haemorrhage and cerebral injury. Neuropathol Appl Neurobiol. 2010 Aug; 36(5):448-58.
Score: 0.008
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Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity. Cardiovasc Res. 2010 Sep 01; 87(4):732-9.
Score: 0.008
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Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase. Stroke. 2009 Jun; 40(6):2191-8.
Score: 0.008
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Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H946-56.
Score: 0.008
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The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach. Am J Pathol. 2009 Jan; 174(1):34-43.
Score: 0.008
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ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. Oncogene. 2009 Feb 05; 28(5):638-50.
Score: 0.007
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Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008 Aug; 8(2):157-68.
Score: 0.007
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Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone. J Neurosci Res. 2008 May 15; 86(7):1482-500.
Score: 0.007
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Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circ Res. 2008 Mar 14; 102(5):519-28.
Score: 0.007
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Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2325-30.
Score: 0.007
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Paucity of pericytes in germinal matrix vasculature of premature infants. J Neurosci. 2007 Oct 31; 27(44):12012-24.
Score: 0.007
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CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2210-8.
Score: 0.007
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Angiogenic inhibition reduces germinal matrix hemorrhage. Nat Med. 2007 Apr; 13(4):477-85.
Score: 0.007
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Cigarette smoke-induced proinflammatory alterations in the endothelial phenotype: role of NAD(P)H oxidase activation. Am J Physiol Heart Circ Physiol. 2007 Jan; 292(1):H130-9.
Score: 0.007
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Comparison of endothelial function, O2-* and H2O2 production, and vascular oxidative stress resistance between the longest-living rodent, the naked mole rat, and mice. Am J Physiol Heart Circ Physiol. 2006 Dec; 291(6):H2698-704.
Score: 0.007
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Transcriptional basis for exercise limitation in male eNOS-knockout mice with age: heart failure and the fetal phenotype. Am J Physiol Heart Circ Physiol. 2005 Oct; 289(4):H1399-407.
Score: 0.006
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Vascular inflammation in aging. Herz. 2004 Dec; 29(8):733-40.
Score: 0.006
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Premature death and age-related cardiac dysfunction in male eNOS-knockout mice. J Mol Cell Cardiol. 2004 Sep; 37(3):671-80.
Score: 0.006
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Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system. Am J Pathol. 2004 Jul; 165(1):219-26.
Score: 0.006
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High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. Circulation. 2003 Sep 09; 108(10):1253-8.
Score: 0.005
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Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase. Arterioscler Thromb Vasc Biol. 2003 Mar 01; 23(3):418-24.
Score: 0.005
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Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2282-7.
Score: 0.005
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Cyclosporin A does not block exercise-induced cardiac hypertrophy. Med Sci Sports Exerc. 2002 Aug; 34(8):1249-54.
Score: 0.005
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Impaired nitric oxide-mediated flow-induced coronary dilation in hyperhomocysteinemia: morphological and functional evidence for increased peroxynitrite formation. Am J Pathol. 2002 Jul; 161(1):145-53.
Score: 0.005
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Increases in endothelial Ca(2+) activate K(Ca) channels and elicit EDHF-type arteriolar dilation via gap junctions. Am J Physiol Heart Circ Physiol. 2002 May; 282(5):H1760-7.
Score: 0.005