William Sonntag to Aging
This is a "connection" page, showing publications William Sonntag has written about Aging.
Connection Strength
12.368
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Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice. J Lipid Res. 2020 10; 61(10):1308-1319.
Score: 0.408
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Simultaneous assessment of cognitive function, circadian rhythm, and spontaneous activity in aging mice. Geroscience. 2018 04; 40(2):123-137.
Score: 0.350
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GeroScience: understanding the interaction of processes of aging and chronic diseases. Age (Dordr). 2016 12; 38(5-6):377-378.
Score: 0.317
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Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice. Age (Dordr). 2016 Apr; 38(2):38.
Score: 0.302
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Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment. J Gerontol A Biol Sci Med Sci. 2016 Jan; 71(1):13-20.
Score: 0.296
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IGF-1 Regulates Vertebral Bone Aging Through Sex-Specific and Time-Dependent Mechanisms. J Bone Miner Res. 2016 Feb; 31(2):443-54.
Score: 0.291
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Brain and cerebrovascular aging--new mechanisms and insights. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1307-10.
Score: 0.275
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Growth hormone, insulin-like growth factor-1 and the aging brain. Exp Gerontol. 2015 Aug; 68:76-81.
Score: 0.273
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Endothelin-1-induced focal cerebral ischemia in the growth hormone/IGF-1 deficient Lewis Dwarf rat. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1353-62.
Score: 0.270
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Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):587-98.
Score: 0.231
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Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):611-25.
Score: 0.230
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Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence. J Endocrinol. 2011 Oct; 211(1):27-37.
Score: 0.218
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Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience. 2011 Jun 30; 185:50-60.
Score: 0.215
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Basal and hypercapnia-altered cerebrovascular perfusion predict mild cognitive impairment in aging rodents. Neuroscience. 2009 Dec 15; 164(3):918-28.
Score: 0.192
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Cognitive performance and age-related changes in the hippocampal proteome. Neuroscience. 2009 Mar 03; 159(1):183-95.
Score: 0.183
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Does senescence give rise to disease? Mech Ageing Dev. 2008 Dec; 129(12):693-9.
Score: 0.181
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Effects of short-term treadmill exercise training or growth hormone supplementation on diastolic function and exercise tolerance in old rats. J Gerontol A Biol Sci Med Sci. 2008 Sep; 63(9):911-20.
Score: 0.179
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Aging reduces hypoxia-induced microvascular growth in the rodent hippocampus. J Gerontol A Biol Sci Med Sci. 2008 Jan; 63(1):12-20.
Score: 0.171
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Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats. J Gerontol A Biol Sci Med Sci. 2006 Jan; 61(1):28-35.
Score: 0.149
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Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus. Mech Ageing Dev. 2006 Jan; 127(1):57-63.
Score: 0.147
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Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging. Ageing Res Rev. 2005 May; 4(2):195-212.
Score: 0.142
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Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span. Endocrinology. 2005 Jul; 146(7):2920-32.
Score: 0.141
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Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learning. Neuroscience. 2004; 129(1):119-27.
Score: 0.130
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A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan. Trends Genet. 2002 Jun; 18(6):295-301.
Score: 0.116
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Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination. J Gerontol A Biol Sci Med Sci. 2002 May; 57(5):B177-88.
Score: 0.116
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Growth hormone, insulin-like growth factor-1 and the aging cardiovascular system. Cardiovasc Res. 2002 Apr; 54(1):25-35.
Score: 0.115
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Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function. Geroscience. 2021 10; 43(5):2183-2203.
Score: 0.111
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype. Geroscience. 2021 10; 43(5):2387-2394.
Score: 0.110
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Growth hormone reverses age-related cardiac myofilament dysfunction in rats. Am J Physiol Heart Circ Physiol. 2001 Aug; 281(2):H915-22.
Score: 0.110
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Growth hormone increases regional coronary blood flow and capillary density in aged rats. J Gerontol A Biol Sci Med Sci. 2001 Aug; 56(8):B364-71.
Score: 0.110
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Assessment of physical function in aging rodents: a strategy for improving preclinical testing. Exp Aging Res. 2001 Jul-Sep; 27(3):271-82.
Score: 0.109
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Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals. Endocrinology. 2001 Jan; 142(1):506-9.
Score: 0.105
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The effects of growth hormone and IGF-1 deficiency on cerebrovascular and brain ageing. J Anat. 2000 Nov; 197 Pt 4:575-85.
Score: 0.104
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Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis Rheum. 2000 Sep; 43(9):2110-20.
Score: 0.103
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Age-related synaptic changes in sensorimotor cortex of the Brown Norway X fischer 344 rat. Brain Res. 2000 Jul 28; 872(1-2):125-33.
Score: 0.102
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Age and insulin-like growth factor-1 modulate N-methyl-D-aspartate receptor subtype expression in rats. Brain Res Bull. 2000 Mar 01; 51(4):331-8.
Score: 0.099
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Chronic [D-Ala2]-growth hormone-releasing hormone administration attenuates age-related deficits in spatial memory. J Gerontol A Biol Sci Med Sci. 2000 Feb; 55(2):B106-12.
Score: 0.099
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Pleiotropic effects of growth hormone and insulin-like growth factor (IGF)-1 on biological aging: inferences from moderate caloric-restricted animals. J Gerontol A Biol Sci Med Sci. 1999 Dec; 54(12):B521-38.
Score: 0.098
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Accelerated decline in cognition in a mouse model of increased oxidative stress. Geroscience. 2019 10; 41(5):591-607.
Score: 0.097
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Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice. Geroscience. 2019 04; 41(2):185-208.
Score: 0.094
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Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227.
Score: 0.094
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Age-related decline in peripheral vascular health predicts cognitive impairment. Geroscience. 2019 04; 41(2):125-136.
Score: 0.094
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Effects of moderate caloric restriction on cortical microvascular density and local cerebral blood flow in aged rats. Neurobiol Aging. 1999 Mar-Apr; 20(2):191-200.
Score: 0.093
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Alterations in insulin-like growth factor-1 gene and protein expression and type 1 insulin-like growth factor receptors in the brains of ageing rats. Neuroscience. 1999 Jan; 88(1):269-79.
Score: 0.092
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Insulin-like growth factor-1 ameliorates age-related behavioral deficits. Neuroscience. 1998 Dec; 87(3):559-69.
Score: 0.091
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Distribution and levels of insulin-like growth factor I mRNA across the life span in the Brown Norway x Fischer 344 rat brain. Brain Res. 1998 Aug 31; 804(1):79-86.
Score: 0.090
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Age-related focal loss of contractile vascular smooth muscle cells in retinal arterioles is accelerated by caveolin-1 deficiency. Neurobiol Aging. 2018 11; 71:1-12.
Score: 0.089
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):853-863.
Score: 0.088
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Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-ß uptake in astrocytes. Mol Metab. 2018 03; 9:141-155.
Score: 0.086
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Decreases in cerebral microvasculature with age are associated with the decline in growth hormone and insulin-like growth factor 1. Endocrinology. 1997 Aug; 138(8):3515-20.
Score: 0.083
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Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging. J Neuroinflammation. 2017 07 21; 14(1):141.
Score: 0.083
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Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.
Score: 0.081
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Growth hormone-induced nuclear translocation of Stat-3 decreases with age: modulation by caloric restriction. Am J Physiol. 1996 Nov; 271(5 Pt 1):E903-9.
Score: 0.079
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Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
Score: 0.078
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IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
Score: 0.078
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Effects of age and insulin-like growth factor-1 on rat neurotrophin receptor expression after nerve injury. Muscle Nerve. 2016 10; 54(4):769-75.
Score: 0.078
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Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation. Age (Dordr). 2016 Jun; 38(3):49.
Score: 0.076
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Moderate caloric restriction prevents the age-related decline in growth hormone receptor signal transduction. J Gerontol A Biol Sci Med Sci. 1996 Mar; 51(2):B167-74.
Score: 0.075
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CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging. J Gerontol A Biol Sci Med Sci. 2017 01; 72(1):16-29.
Score: 0.075
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Decreases in growth hormone receptor signal transduction contribute to the decline in insulin-like growth factor I gene expression with age. Endocrinology. 1995 Oct; 136(10):4551-7.
Score: 0.073
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IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. 2015 Dec; 14(6):1034-44.
Score: 0.072
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Moderate caloric restriction alters the subcellular distribution of somatostatin mRNA and increases growth hormone pulse amplitude in aged animals. Neuroendocrinology. 1995 May; 61(5):601-8.
Score: 0.071
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Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):527-30.
Score: 0.071
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Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell. 2015 Jun; 14(3):400-8.
Score: 0.070
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Effect of in utero ethanol exposure on the postnatal ontogeny of insulin-like growth factor-1, and type-1 and type-2 insulin-like growth factor receptors in the rat brain. Neuroscience. 1994 Nov; 63(2):579-89.
Score: 0.069
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Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2015 Jun; 70(6):665-74.
Score: 0.068
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Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1311-24.
Score: 0.067
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Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
Score: 0.067
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Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52.
Score: 0.067
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Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. Am J Physiol Heart Circ Physiol. 2014 Feb; 306(3):H299-308.
Score: 0.065
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Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease. J Gerontol A Biol Sci Med Sci. 2014 Oct; 69(10):1212-26.
Score: 0.064
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Moderate caloric restriction increases type 1 IGF receptors and protein synthesis in aging rats. Mech Ageing Dev. 1993 Oct 01; 71(1-2):59-71.
Score: 0.064
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Comparison of protein synthesis in brain and peripheral tissue during aging. Relationship to insulin-like growth factor-1 and type 1 IGF receptors. Ann N Y Acad Sci. 1993 Aug 27; 692:253-5.
Score: 0.063
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Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in ß-amyloid generation and Alzheimer's disease. Am J Physiol Heart Circ Physiol. 2013 Oct 15; 305(8):H1120-30.
Score: 0.063
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Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1732-42.
Score: 0.063
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Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus. Cell Mol Neurobiol. 2013 May; 33(4):483-8.
Score: 0.061
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The regulation and mechanisms of action of growth hormone and insulin-like growth factor 1 during normal ageing. J Reprod Fertil Suppl. 1993; 46:87-98.
Score: 0.061
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Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68(8):877-91.
Score: 0.060
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Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation. J Gerontol A Biol Sci Med Sci. 2013 Jul; 68(7):780-92.
Score: 0.060
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Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. J Gerontol A Biol Sci Med Sci. 2013 Jun; 68(6):652-60.
Score: 0.060
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Effects of aging and dietary restriction on tissue protein synthesis: relationship to plasma insulin-like growth factor-1. J Gerontol. 1992 Sep; 47(5):B159-63.
Score: 0.059
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Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa). J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):359-67.
Score: 0.059
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Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging. J Mol Neurosci. 2012 Sep; 48(1):111-26.
Score: 0.058
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Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory. J Neurochem. 2012 Apr; 121(1):77-98.
Score: 0.057
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Attenuation of Fos-like immunoreactivity induced by a single electroconvulsive shock in brains of aging mice. Brain Res. 1991 Dec 20; 567(2):204-11.
Score: 0.056
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Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats. Behav Brain Res. 2012 Feb 01; 227(1):258-64.
Score: 0.056
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Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging. J Gerontol A Biol Sci Med Sci. 2012 Apr; 67(4):313-29.
Score: 0.056
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Growth hormone modulates hippocampal excitatory synaptic transmission and plasticity in old rats. Neurobiol Aging. 2012 Sep; 33(9):1938-49.
Score: 0.056
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Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment. J Neuroinflammation. 2011 Oct 11; 8:138.
Score: 0.056
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Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins. J Gerontol. 1991 Sep; 46(5):B180-7.
Score: 0.055
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Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. J Gerontol A Biol Sci Med Sci. 2011 Aug; 66(8):866-75.
Score: 0.054
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Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H363-72.
Score: 0.054
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Age-related alterations in retinal neurovascular and inflammatory transcripts. Mol Vis. 2011; 17:1261-74.
Score: 0.054
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Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal. J Gerontol A Biol Sci Med Sci. 2011 Jul; 66(7):741-50.
Score: 0.054
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Effect of aging on GHRF-induced growth hormone release from anterior pituitary cells in primary culture. J Gerontol. 1991 Mar; 46(2):B72-7.
Score: 0.053
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An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe. Free Radic Res. 2011 Feb; 45(2):237-47.
Score: 0.052
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Mitochondria and aging in the vascular system. J Mol Med (Berl). 2010 Oct; 88(10):1021-7.
Score: 0.051
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Somatostatin gene expression in hypothalamus and cortex of aging male rats. Neurobiol Aging. 1990 Jul-Aug; 11(4):409-16.
Score: 0.051
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Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci. 2010 Oct; 65(10):1028-41.
Score: 0.051
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Impaired bladder function in aging male rats. J Urol. 2010 Jul; 184(1):378-85.
Score: 0.050
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Aging attenuates radiation-induced expression of pro-inflammatory mediators in rat brain. Neurosci Lett. 2010 May 31; 476(2):89-93.
Score: 0.050
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Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome. J Neurochem. 2010 Jun; 113(6):1577-88.
Score: 0.050
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Effect of locally delivered IGF-1 on nerve regeneration during aging: an experimental study in rats. Muscle Nerve. 2010 Mar; 41(3):335-41.
Score: 0.050
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Increased pituitary response to somatostatin in aging male rats: relationship to somatostatin receptor number and affinity. Neuroendocrinology. 1989 Nov; 50(5):489-94.
Score: 0.049
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Early-onset GH deficiency results in spatial memory impairment in mid-life and is prevented by GH supplementation. J Endocrinol. 2010 Jan; 204(1):31-6.
Score: 0.048
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Adult-onset deficiency in growth hormone and insulin-like growth factor-I alters oligodendrocyte turnover in the corpus callosum. Glia. 2009 Aug 01; 57(10):1062-71.
Score: 0.048
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How age impairs the response of the neuromuscular junction to nerve transection and repair: An experimental study in rats. J Orthop Res. 2009 Mar; 27(3):385-93.
Score: 0.046
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Growth hormone releasing hormone induced release of growth hormone in aging male rats: dependence on pharmacological manipulation and endogenous somatostatin release. Neuroendocrinology. 1988 Jun; 47(6):482-8.
Score: 0.044
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Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability. Exp Neurol. 2008 May; 211(1):141-9.
Score: 0.043
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Lifelong caloric restriction and interleukin-6 secretion from adipose tissue: effects on physical performance decline in aged rats. J Gerontol A Biol Sci Med Sci. 2007 Oct; 62(10):1082-7.
Score: 0.042
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Diminished diurnal secretion of adrenocorticotropin (ACTH), but not corticosterone, in old male rats: possible relation to increased adrenal sensitivity to ACTH in vivo. Endocrinology. 1987 Jun; 120(6):2308-15.
Score: 0.041
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Increased secretion of somatostatin-28 from hypothalamic neurons of aged rats in vitro. Brain Res. 1986 Aug 20; 380(2):229-34.
Score: 0.039
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Growth hormone restores protein synthesis in skeletal muscle of old male rats. J Gerontol. 1985 Nov; 40(6):689-94.
Score: 0.037
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Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems. Physiol Genomics. 2005 Nov 17; 23(3):311-7.
Score: 0.036
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Differential effects of aging and insulin-like growth factor-1 on synapses in CA1 of rat hippocampus. Cereb Cortex. 2005 May; 15(5):571-7.
Score: 0.034
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Biomarkers of aging: from primitive organisms to humans. J Gerontol A Biol Sci Med Sci. 2004 Jun; 59(6):B560-7.
Score: 0.033
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Decreased ability of old male rats to secrete luteinizing hormone (LH) is not due to alterations in pituitary LH-releasing hormone receptors. Endocrinology. 1984 May; 114(5):1657-64.
Score: 0.033
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Impaired ability of old male rats to secrete growth hormone in vivo but not in vitro in response to hpGRF(1-44). Endocrinology. 1983 Dec; 113(6):2305-7.
Score: 0.032
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Microvascular plasticity in aging. Ageing Res Rev. 2003 Apr; 2(2):149-68.
Score: 0.031
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Insulin-like growth factor-1 does not ameliorate the age-related decline in presumptive inhibitory synapses in layer 2 of rat sensorimotor cortex. Prog Neuropsychopharmacol Biol Psychiatry. 2002 Jan; 26(1):97-102.
Score: 0.028
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IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging. Geroscience. 2021 04; 43(2):901-911.
Score: 0.027
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Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis. Neuroscience. 2001; 107(4):603-13.
Score: 0.026
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Effects of age and insulin-like growth factor-1 on neuron and synapse numbers in area CA3 of hippocampus. Neuroscience. 2001; 107(2):231-8.
Score: 0.026
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Reproduction in aging normal and neonatally androgenized female rats. J Comp Physiol Psychol. 1980 Jun; 94(3):556-63.
Score: 0.025
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Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. 2018 04; 17(2).
Score: 0.022
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Effect of age and caloric restriction on insulin receptor binding and glucose transporter levels in aging rats. Exp Gerontol. 1997 Nov-Dec; 32(6):671-84.
Score: 0.021
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[Polyploidisation - a phenomenon of aging? (author's transl)]. Aktuelle Gerontol. 1977 Oct; 7(10):521-7.
Score: 0.021
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L-type Ca2+ channel-insulin-like growth factor-1 receptor signaling impairment in aging rat skeletal muscle. Biochem Biophys Res Commun. 1997 Jun 27; 235(3):784-9.
Score: 0.021
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[The vascularisation of the granulation tissue in different ages. - Its importance for wound healing (author's transl)]. Aktuelle Gerontol. 1977 May; 7(5):253-6.
Score: 0.020
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Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen. J Gerontol A Biol Sci Med Sci. 1995 Nov; 50(6):B337-41.
Score: 0.018
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Insulin-like growth factor-1 stimulation of protein synthesis is attenuated in cerebral cortex of aging rats. Neuroscience. 1995 Apr; 65(3):805-13.
Score: 0.018
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IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97.
Score: 0.017
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A heart that beats for 500 years: age-related changes in cardiac proteasome activity, oxidative protein damage and expression of heat shock proteins, inflammatory factors, and mitochondrial complexes in Arctica islandica, the longest-living noncolonial animal. J Gerontol A Biol Sci Med Sci. 2014 Dec; 69(12):1448-61.
Score: 0.016
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Role of 20-HETE, TRPC channels, and BKCa in dysregulation of pressure-induced Ca2+ signaling and myogenic constriction of cerebral arteries in aged hypertensive mice. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1698-708.
Score: 0.016
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Mitochondrial protection by resveratrol. Exerc Sport Sci Rev. 2011 Jul; 39(3):128-32.
Score: 0.014
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Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production. Age (Dordr). 2011 Sep; 33(3):261-74.
Score: 0.013
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Dendritic stability in a model of adult-onset IGF-I deficiency. Growth Horm IGF Res. 2005 Oct; 15(5):337-48.
Score: 0.009
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Pituitary growth hormone and hypothalamic somatostatin in young female rats versus old constant estrous female rats. Experientia. 1985 May 15; 41(5):653-4.
Score: 0.009
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Immunoreactive beta-endorphin in the plasma, pituitary and hypothalamus of young female rats on the day of estrus and intact and chronically castrated old constant estrous female rats. Life Sci. 1983 Sep 05; 33(10):993-9.
Score: 0.008
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Effects of ovariectomy and steroid replacement on hypothalamic LHRH content in aging female rats. Neurobiol Aging. 1983; 4(1):53-7.
Score: 0.008
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Physical performance and longevity in aged rats. J Gerontol A Biol Sci Med Sci. 2002 May; 57(5):B193-7.
Score: 0.007
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Caloric restricted male rats demonstrate fewer synapses in layer 2 of sensorimotor cortex. Brain Res. 2002 Mar 22; 931(1):32-40.
Score: 0.007
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Effects of CNS active drugs and somatostatin antiserum on growth hormone release in young and old male rats. Neuroendocrinology. 1981 Aug; 33(2):73-8.
Score: 0.007
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Maintenance by L-DOPA treatment of estrous cycles and LH response to estrogen in aging female rats. Exp Aging Res. 1980 Dec; 6(6):547-54.
Score: 0.007
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Decreased pulsatile release of growth hormone in old male rats. Endocrinology. 1980 Dec; 107(6):1875-9.
Score: 0.007
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Immunoreactive beta-endorphin in the plasma, pituitary and hypothalamus of young and old male rats. Neurobiol Aging. 1981; 2(4):281-4.
Score: 0.002
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Reduced ability of naloxone to stimulate LH and testosterone release in aging male rats; possible relation to increase in hypothalamic met5-enkephalin. Life Sci. 1980 Sep 01; 27(9):747-53.
Score: 0.002