Adam Duerfeldt to Humans
This is a "connection" page, showing publications Adam Duerfeldt has written about Humans.
Connection Strength
0.364
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The cGAS-STING pathway in diabetic retinopathy and age-related macular degeneration. Future Med Chem. 2023 Apr; 15(8):717-729.
Score: 0.048
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Identification of ClpP Dual Isoform Disruption as an Antisporulation Strategy for Clostridioides difficile. J Bacteriol. 2022 02 15; 204(2):e0041121.
Score: 0.044
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Small-Molecule Modulation of PPARs for the Treatment of Prevalent Vascular Retinal Diseases. Int J Mol Sci. 2020 Dec 04; 21(23).
Score: 0.041
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Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARa Agonists as Leads for Retinal Disorders. J Med Chem. 2020 03 26; 63(6):2854-2876.
Score: 0.039
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First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors. Bioorg Med Chem Lett. 2019 07 15; 29(14):1836-1841.
Score: 0.037
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Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARa selective agonists: New leads for oculovascular conditions. Bioorg Med Chem Lett. 2018 09 01; 28(16):2717-2722.
Score: 0.034
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Development of a Grp94 inhibitor. J Am Chem Soc. 2012 Jun 13; 134(23):9796-804.
Score: 0.023
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Design, synthesis, and biological evaluation of conformationally constrained cis-amide Hsp90 inhibitors. Org Lett. 2009 Jun 04; 11(11):2353-6.
Score: 0.018
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Hydrating for resistance to radicicol. ACS Chem Biol. 2009 Apr 17; 4(4):245-7.
Score: 0.018
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Property space mapping of Pseudomonas aeruginosa permeability to small molecules. Sci Rep. 2022 05 17; 12(1):8220.
Score: 0.011
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CpxA Phosphatase Inhibitor Activates CpxRA and Is a Potential Treatment for Uropathogenic Escherichia coli in a Murine Model of Infection. Microbiol Spectr. 2022 04 27; 10(2):e0243021.
Score: 0.011
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Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding. J Med Chem. 2018 04 12; 61(7):2793-2805.
Score: 0.008
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Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold. J Med Chem. 2016 Apr 14; 59(7):3471-88.
Score: 0.007
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Grp94 Protein Delivers ?-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation. J Biol Chem. 2016 Apr 29; 291(18):9526-39.
Score: 0.007
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Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism. J Biol Chem. 2012 Nov 23; 287(48):40661-9.
Score: 0.006
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Synthesis and biological evaluation of arylated novobiocin analogs as Hsp90 inhibitors. Bioorg Med Chem Lett. 2011 Dec 01; 21(23):7170-4.
Score: 0.005
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Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors. Bioorg Med Chem Lett. 2009 Dec 15; 19(24):6845-50.
Score: 0.005