Kevin Brown to Genetic Predisposition to Disease
This is a "connection" page, showing publications Kevin Brown has written about Genetic Predisposition to Disease.
Connection Strength
4.106
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Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nat Commun. 2020 06 01; 11(1):2718.
Score: 0.535
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Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes. Genome Res. 2018 11; 28(11):1621-1635.
Score: 0.478
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A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 2011 Nov 13; 480(7375):99-103.
Score: 0.296
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Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma. Nat Genet. 2009 Aug; 41(8):873-5.
Score: 0.252
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Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet. 2008 Jul; 40(7):838-40.
Score: 0.232
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Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nat Genet. 2024 May; 56(5):809-818.
Score: 0.175
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A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. Am J Hum Genet. 2021 09 02; 108(9):1611-1630.
Score: 0.145
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Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms. Am J Hum Genet. 2021 09 02; 108(9):1631-1646.
Score: 0.145
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Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Nat Genet. 2020 05; 52(5):494-504.
Score: 0.133
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Sex specific associations in genome wide association analysis of renal cell carcinoma. Eur J Hum Genet. 2019 10; 27(10):1589-1598.
Score: 0.125
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A Dynamic Cis-Regulation Pattern Underlying Epithelial Ovarian Cancer Susceptibility. Cancer Res. 2019 02 01; 79(3):439-440.
Score: 0.122
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Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Hum Mol Genet. 2018 12 01; 27(23):4145-4156.
Score: 0.121
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Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Nat Commun. 2017 06 09; 8:15724.
Score: 0.109
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Germline TERT promoter mutations are rare in familial melanoma. Fam Cancer. 2016 Jan; 15(1):139-44.
Score: 0.099
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A recurrent germline BAP1 mutation and extension of the BAP1 tumor predisposition spectrum to include basal cell carcinoma. Clin Genet. 2015 Sep; 88(3):267-72.
Score: 0.091
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Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions. Int J Cancer. 2015 Mar 15; 136(6):1351-60.
Score: 0.090
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Assessment of PALB2 as a candidate melanoma susceptibility gene. PLoS One. 2014; 9(6):e100683.
Score: 0.089
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POT1 loss-of-function variants predispose to familial melanoma. Nat Genet. 2014 May; 46(5):478-481.
Score: 0.087
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A variant in FTO shows association with melanoma risk not due to BMI. Nat Genet. 2013 Apr; 45(4):428-32, 432e1.
Score: 0.081
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Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet. 2011 Oct 09; 43(11):1108-13.
Score: 0.074
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Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet. 2011 Dec 15; 20(24):5012-23.
Score: 0.073
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Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies. PLoS One. 2010 May 28; 5(5):e10858.
Score: 0.067
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Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet. 2009 Aug; 41(8):920-5.
Score: 0.063
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Rare germline deleterious variants increase susceptibility for lung cancer. Hum Mol Genet. 2022 Oct 10; 31(20):3558-3565.
Score: 0.039
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Defining novel causal SNPs and linked phenotypes at melanoma-associated loci. Hum Mol Genet. 2022 08 25; 31(17):2845-2856.
Score: 0.039
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Functional annotation and investigation of the 10q24.33 melanoma risk locus identifies a common variant that influences transcriptional regulation of OBFC1. Hum Mol Genet. 2022 03 21; 31(6):863-874.
Score: 0.038
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Integrated Analysis of Coexpression and Exome Sequencing to Prioritize Susceptibility Genes for Familial Cutaneous Melanoma. J Invest Dermatol. 2022 09; 142(9):2464-2475.e5.
Score: 0.038
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Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus. Am J Hum Genet. 2021 09 02; 108(9):1590-1610.
Score: 0.036
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Evaluation of the contribution of germline variants in BRCA1 and BRCA2 to uveal and cutaneous melanoma. Melanoma Res. 2019 10; 29(5):483-490.
Score: 0.032
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Assessing the Incremental Contribution of Common Genomic Variants to Melanoma Risk Prediction in Two Population-Based Studies. J Invest Dermatol. 2018 12; 138(12):2617-2624.
Score: 0.029
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Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma. Eur Urol. 2017 11; 72(5):747-754.
Score: 0.028
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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nat Commun. 2017 05 02; 8:15034.
Score: 0.027
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Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nat Genet. 2015 Sep; 47(9):987-995.
Score: 0.024
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Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma. J Natl Cancer Inst. 2015 Feb; 107(2).
Score: 0.023
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Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis. 2014 Sep; 35(9):2097-101.
Score: 0.022
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A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers. PLoS One. 2013; 8(8):e72144.
Score: 0.021
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Occurrence of NKX3.1 C154T polymorphism in men with and without prostate cancer and studies of its effect on protein function. Cancer Res. 2002 May 01; 62(9):2654-9.
Score: 0.010
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Variation in the ESR1 and ESR2 genes and genetic susceptibility to anorexia nervosa. Mol Psychiatry. 2002; 7(1):86-9.
Score: 0.009
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No missense mutation of WKL1 in a subgroup of probands with schizophrenia. Mol Psychiatry. 2002; 7(4):419-23.
Score: 0.009