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This is a "connection" page, showing publications co-authored by Stefano Tarantini and Zoltan Ungvari.
Stefano Tarantini
Connection Strength
16.148
Zoltan Ungvari
  1. Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice. Geroscience. 2021 10; 43(5):2427-2440.
    View in: PubMed
    Score: 0.789
  2. Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice. Geroscience. 2021 10; 43(5):2611-2619.
    View in: PubMed
    Score: 0.788
  3. IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging. Geroscience. 2021 04; 43(2):901-911.
    View in: PubMed
    Score: 0.764
  4. Midlife Obesity Impairs Neurovascular Coupling Responses. Obesity (Silver Spring). 2021 01; 29(1):17.
    View in: PubMed
    Score: 0.751
  5. Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging. Geroscience. 2019 10; 41(5):533-542.
    View in: PubMed
    Score: 0.696
  6. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019 06; 24:101192.
    View in: PubMed
    Score: 0.669
  7. Correction to: Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2018 04; 40(2):219.
    View in: PubMed
    Score: 0.624
  8. Treatment with the mitochondrial-targeted antioxidant peptide SS-31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice. Aging Cell. 2018 04; 17(2).
    View in: PubMed
    Score: 0.617
  9. Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice. Geroscience. 2017 12; 39(5-6):601-614.
    View in: PubMed
    Score: 0.611
  10. Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype. Aging Cell. 2017 06; 16(3):469-479.
    View in: PubMed
    Score: 0.580
  11. Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling. Geroscience. 2022 04; 44(2):953-981.
    View in: PubMed
    Score: 0.204
  12. Cerebral venous congestion exacerbates cerebral microhemorrhages in mice. Geroscience. 2022 04; 44(2):805-816.
    View in: PubMed
    Score: 0.202
  13. Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission. Geroscience. 2021 10; 43(5):2305-2320.
    View in: PubMed
    Score: 0.198
  14. Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype. Geroscience. 2021 10; 43(5):2387-2394.
    View in: PubMed
    Score: 0.197
  15. Early manifestation of gait alterations in the Tg2576 mouse model of Alzheimer's disease. Geroscience. 2021 08; 43(4):1947-1957.
    View in: PubMed
    Score: 0.195
  16. Hypertension-induced cognitive impairment: from pathophysiology to public health. Nat Rev Nephrol. 2021 Oct; 17(10):639-654.
    View in: PubMed
    Score: 0.195
  17. Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography. Am J Physiol Heart Circ Physiol. 2021 04 01; 320(4):H1370-H1392.
    View in: PubMed
    Score: 0.190
  18. Obesity-induced cognitive impairment in older adults: a microvascular perspective. Am J Physiol Heart Circ Physiol. 2021 02 01; 320(2):H740-H761.
    View in: PubMed
    Score: 0.188
  19. Increases in hypertension-induced cerebral microhemorrhages exacerbate gait dysfunction in a mouse model of Alzheimer's disease. Geroscience. 2020 12; 42(6):1685-1698.
    View in: PubMed
    Score: 0.184
  20. Companion animals likely do not spread COVID-19 but may get infected themselves. Geroscience. 2020 10; 42(5):1229-1236.
    View in: PubMed
    Score: 0.183
  21. Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain. Geroscience. 2020 04; 42(2):429-444.
    View in: PubMed
    Score: 0.179
  22. Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood. Geroscience. 2020 04; 42(2):727-748.
    View in: PubMed
    Score: 0.179
  23. Mechanisms of Vascular Aging, A Geroscience Perspective: JACC Focus Seminar. J Am Coll Cardiol. 2020 03 03; 75(8):931-941.
    View in: PubMed
    Score: 0.178
  24. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020 04; 42(2):527-546.
    View in: PubMed
    Score: 0.177
  25. Pharmacological or genetic depletion of senescent astrocytes prevents whole brain irradiation-induced impairment of neurovascular coupling responses protecting cognitive function in mice. Geroscience. 2020 04; 42(2):409-428.
    View in: PubMed
    Score: 0.177
  26. Cerebral venous congestion promotes blood-brain barrier disruption and neuroinflammation, impairing cognitive function in mice. Geroscience. 2019 10; 41(5):575-589.
    View in: PubMed
    Score: 0.174
  27. Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases. Geroscience. 2019 12; 41(6):727-738.
    View in: PubMed
    Score: 0.174
  28. Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice. Geroscience. 2019 12; 41(6):711-725.
    View in: PubMed
    Score: 0.174
  29. Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice. Geroscience. 2019 10; 41(5):609-617.
    View in: PubMed
    Score: 0.174
  30. Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation. Front Genet. 2019; 10:898.
    View in: PubMed
    Score: 0.173
  31. Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. Geroscience. 2019 08; 41(4):419-439.
    View in: PubMed
    Score: 0.172
  32. Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability. J Gerontol A Biol Sci Med Sci. 2019 08 16; 74(9):1417-1421.
    View in: PubMed
    Score: 0.171
  33. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 10; 41(5):619-630.
    View in: PubMed
    Score: 0.169
  34. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 04; 41(2):209-227.
    View in: PubMed
    Score: 0.168
  35. Role of endothelial NAD+ deficiency in age-related vascular dysfunction. Am J Physiol Heart Circ Physiol. 2019 06 01; 316(6):H1253-H1266.
    View in: PubMed
    Score: 0.167
  36. Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2019 05 01; 316(5):H1124-H1140.
    View in: PubMed
    Score: 0.166
  37. Advances and challenges in geroscience research: An update. Physiol Int. 2018 Dec 01; 105(4):298-308.
    View in: PubMed
    Score: 0.163
  38. Repeated Valsalva maneuvers promote symptomatic manifestations of cerebral microhemorrhages: implications for the pathogenesis of vascular cognitive impairment in older adults. Geroscience. 2018 12; 40(5-6):485-496.
    View in: PubMed
    Score: 0.161
  39. Mechanisms of Vascular Aging. Circ Res. 2018 09 14; 123(7):849-867.
    View in: PubMed
    Score: 0.161
  40. Endothelial dysfunction and angiogenesis impairment in the ageing vasculature. Nat Rev Cardiol. 2018 09; 15(9):555-565.
    View in: PubMed
    Score: 0.160
  41. Assessment of endothelial function in leptomeningeal arterioles derived from patients with Alzheimer's disease and vascular cognitive impairment. Am J Physiol Heart Circ Physiol. 2018 10 01; 315(4):H790-H793.
    View in: PubMed
    Score: 0.158
  42. Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype. J Gerontol A Biol Sci Med Sci. 2018 06 14; 73(7):853-863.
    View in: PubMed
    Score: 0.158
  43. Connective tissue growth factor (CTGF) in age-related vascular pathologies. Geroscience. 2017 12; 39(5-6):491-498.
    View in: PubMed
    Score: 0.150
  44. Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment. Geroscience. 2017 Aug; 39(4):385-406.
    View in: PubMed
    Score: 0.148
  45. Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging. Geroscience. 2017 Aug; 39(4):465-473.
    View in: PubMed
    Score: 0.147
  46. Cerebral microhemorrhages: mechanisms, consequences, and prevention. Am J Physiol Heart Circ Physiol. 2017 Jun 01; 312(6):H1128-H1143.
    View in: PubMed
    Score: 0.145
  47. Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence. Geroscience. 2017 02; 39(1):33-42.
    View in: PubMed
    Score: 0.144
  48. Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline. Exp Gerontol. 2017 08; 94:52-58.
    View in: PubMed
    Score: 0.142
  49. Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging. Am J Physiol Heart Circ Physiol. 2017 Jan 01; 312(1):H1-H20.
    View in: PubMed
    Score: 0.141
  50. Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging. Age (Dordr). 2016 Aug; 38(4):273-289.
    View in: PubMed
    Score: 0.140
  51. IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis. Age (Dordr). 2016 Aug; 38(4):239-258.
    View in: PubMed
    Score: 0.140
  52. Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1837-45.
    View in: PubMed
    Score: 0.131
  53. Pharmacologically-induced neurovascular uncoupling is associated with cognitive impairment in mice. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1871-81.
    View in: PubMed
    Score: 0.129
  54. IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging. Aging Cell. 2015 Dec; 14(6):1034-44.
    View in: PubMed
    Score: 0.129
  55. Aging impairs myogenic adaptation to pulsatile pressure in mouse cerebral arteries. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):527-30.
    View in: PubMed
    Score: 0.127
  56. Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell. 2015 Jun; 14(3):400-8.
    View in: PubMed
    Score: 0.125
  57. Aging Exacerbates Pressure-Induced Mitochondrial Oxidative Stress in Mouse Cerebral Arteries. J Gerontol A Biol Sci Med Sci. 2015 Nov; 70(11):1355-9.
    View in: PubMed
    Score: 0.125
  58. IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice. J Cereb Blood Flow Metab. 2014 Dec; 34(12):1887-97.
    View in: PubMed
    Score: 0.122
  59. Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. J Gerontol A Biol Sci Med Sci. 2015 Jun; 70(6):665-74.
    View in: PubMed
    Score: 0.121
  60. Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats. Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H292-306.
    View in: PubMed
    Score: 0.120
  61. Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. Am J Physiol Heart Circ Physiol. 2014 Feb; 306(3):H299-308.
    View in: PubMed
    Score: 0.116
  62. Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1732-42.
    View in: PubMed
    Score: 0.113
  63. Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults. Am J Physiol Heart Circ Physiol. 2022 06 01; 322(6):H924-H935.
    View in: PubMed
    Score: 0.051
  64. Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging. Front Aging Neurosci. 2022; 14:788296.
    View in: PubMed
    Score: 0.051
  65. Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain. Geroscience. 2022 04; 44(2):661-681.
    View in: PubMed
    Score: 0.051
  66. Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses. Sci Rep. 2021 10 25; 11(1):20994.
    View in: PubMed
    Score: 0.050
  67. Sleep deprivation alters task-related changes in functional connectivity of the frontal cortex: A near-infrared spectroscopy study. Brain Behav. 2021 08; 11(8):e02135.
    View in: PubMed
    Score: 0.049
  68. Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults. PLoS One. 2021; 16(5):e0250043.
    View in: PubMed
    Score: 0.048
  69. Whole brain irradiation in mice causes long-term impairment in astrocytic calcium signaling but preserves astrocyte-astrocyte coupling. Geroscience. 2021 02; 43(1):197-212.
    View in: PubMed
    Score: 0.047
  70. Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions. Geroscience. 2019 12; 41(6):813-845.
    View in: PubMed
    Score: 0.044
  71. Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans. Geroscience. 2019 10; 41(5):495-509.
    View in: PubMed
    Score: 0.044
  72. Hypertension Exacerbates Cerebrovascular Oxidative Stress Induced by Mild Traumatic Brain Injury: Protective Effects of the Mitochondria-Targeted Antioxidative Peptide SS-31. J Neurotrauma. 2019 12 01; 36(23):3309-3315.
    View in: PubMed
    Score: 0.043
  73. Age-related impairment of neurovascular coupling responses: a dynamic vessel analysis (DVA)-based approach to measure decreased flicker light stimulus-induced retinal arteriolar dilation in healthy older adults. Geroscience. 2019 06; 41(3):341-349.
    View in: PubMed
    Score: 0.042
  74. Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice. Geroscience. 2019 04; 41(2):185-208.
    View in: PubMed
    Score: 0.042
  75. Age-related decline in peripheral vascular health predicts cognitive impairment. Geroscience. 2019 04; 41(2):125-136.
    View in: PubMed
    Score: 0.042
  76. IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):446-454.
    View in: PubMed
    Score: 0.042
  77. Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):290-298.
    View in: PubMed
    Score: 0.041
  78. Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation. Geroscience. 2018 12; 40(5-6):513-521.
    View in: PubMed
    Score: 0.041
  79. Short-term weight loss reverses obesity-induced microvascular endothelial dysfunction. Geroscience. 2018 Jun 18.
    View in: PubMed
    Score: 0.040
  80. Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol. 2018 07; 17:47-58.
    View in: PubMed
    Score: 0.039
  81. Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease. Geroscience. 2017 Aug; 39(4):359-372.
    View in: PubMed
    Score: 0.037
  82. Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet. Aging (Albany NY). 2016 05; 8(5):899-916.
    View in: PubMed
    Score: 0.034
  83. Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. J Gerontol A Biol Sci Med Sci. 2014 Nov; 69(11):1339-52.
    View in: PubMed
    Score: 0.030
  84. Treatment with the cytochrome P450 ?-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats. Br J Pharmacol. 2013 Apr; 168(8):1878-88.
    View in: PubMed
    Score: 0.028
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.