Jimmy Ballard to Bacterial Toxins
This is a "connection" page, showing publications Jimmy Ballard has written about Bacterial Toxins.
Connection Strength
11.051
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A sequence invariable region in TcdB2 is required for toxin escape from Clostridioides difficile. J Bacteriol. 2024 07 25; 206(7):e0009624.
Score: 0.741
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Discovery of Hippo signaling as a regulator of CSPG4 expression and as a therapeutic target for Clostridioides difficile disease. PLoS Pathog. 2023 03; 19(3):e1011272.
Score: 0.680
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Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production. mBio. 2020 12 22; 11(6).
Score: 0.582
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Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin. J Biol Chem. 2018 02 02; 293(5):1810-1819.
Score: 0.472
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Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB. mBio. 2017 05 16; 8(3).
Score: 0.453
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Exposure of neutralizing epitopes in the carboxyl-terminal domain of TcdB is altered by a proximal hypervariable region. J Biol Chem. 2015 Mar 13; 290(11):6975-85.
Score: 0.386
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Clostridium difficile 027/BI/NAP1 encodes a hypertoxic and antigenically variable form of TcdB. PLoS Pathog. 2013; 9(8):e1003523.
Score: 0.349
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Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood. Infect Immun. 2013 Oct; 81(10):3693-702.
Score: 0.348
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TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing. Mol Microbiol. 2012 Apr; 84(1):66-76.
Score: 0.316
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Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages. Infect Immun. 2011 Aug; 79(8):3302-8.
Score: 0.299
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Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem. 2011 Jun 03; 286(22):19364-72.
Score: 0.297
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Medical microbiology: A toxin contest. Nature. 2010 Oct 07; 467(7316):665-6.
Score: 0.287
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Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile. PLoS Pathog. 2010 Aug 19; 6(8):e1001061.
Score: 0.284
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Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta. Infect Immun. 2008 Nov; 76(11):4895-904.
Score: 0.248
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Critical intermediate steps in Clostridium sordellii lethal toxin-induced apoptosis. Biochem Biophys Res Commun. 2007 Nov 30; 363(4):959-64.
Score: 0.233
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Elucidating the in vivo targets of bacterial toxins. Future Microbiol. 2007 Feb; 2(1):85-92.
Score: 0.222
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Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication. Proc Natl Acad Sci U S A. 2006 Sep 19; 103(38):14176-81.
Score: 0.216
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Cytotoxic activity of Bacillus anthracis protective antigen observed in a macrophage cell line overexpressing ANTXR1. Cell Microbiol. 2006 Aug; 8(8):1272-81.
Score: 0.215
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Variations in lethal toxin and cholesterol-dependent cytolysin production correspond to differences in cytotoxicity among strains of Clostridium sordellii. FEMS Microbiol Lett. 2006 Jun; 259(2):295-302.
Score: 0.212
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Clostridium difficile toxins: mechanism of action and role in disease. Clin Microbiol Rev. 2005 Apr; 18(2):247-63.
Score: 0.196
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Clostridium sordellii lethal toxin is maintained in a multimeric protein complex. Infect Immun. 2004 Jun; 72(6):3366-72.
Score: 0.185
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Clostridioides difficile toxin B subverts germinal center and antibody recall responses by stimulating a drug-treatable CXCR4-dependent mechanism. Cell Rep. 2024 May 28; 43(5):114245.
Score: 0.184
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Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12426-31.
Score: 0.176
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Decreased glycogen synthase kinase 3-beta levels and related physiological changes in Bacillus anthracis lethal toxin-treated macrophages. Cell Microbiol. 2003 Aug; 5(8):523-32.
Score: 0.174
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Mutational analysis of the enzymatic domain of Clostridium difficile toxin B reveals novel inhibitors of the wild-type toxin. Infect Immun. 2003 Jun; 71(6):3294-301.
Score: 0.172
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Clostridium difficile toxin B activates dual caspase-dependent and caspase-independent apoptosis in intoxicated cells. Cell Microbiol. 2002 Jul; 4(7):425-34.
Score: 0.162
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Clostridioides difficile Toxin B Activates Group 3 Innate Lymphocytes. Infect Immun. 2022 04 21; 90(4):e0007322.
Score: 0.159
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pH-enhanced cytopathic effects of Clostridium sordellii lethal toxin. Infect Immun. 2001 Sep; 69(9):5487-93.
Score: 0.153
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Cytosolic delivery and characterization of the TcdB glucosylating domain by using a heterologous protein fusion. Infect Immun. 2001 Jan; 69(1):599-601.
Score: 0.146
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Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies. JCI Insight. 2020 08 20; 5(16).
Score: 0.142
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pH-induced conformational changes in Clostridium difficile toxin B. Infect Immun. 2000 May; 68(5):2470-4.
Score: 0.139
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Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes. PLoS One. 2020; 15(4):e0230782.
Score: 0.139
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Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells. Infect Immun. 1998 Oct; 66(10):4696-9.
Score: 0.125
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Anthrax toxin-mediated delivery in vivo and in vitro of a cytotoxic T-lymphocyte epitope from ovalbumin. Infect Immun. 1998 Feb; 66(2):615-9.
Score: 0.119
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Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients. Clin Vaccine Immunol. 2017 Nov; 24(11).
Score: 0.117
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Anthrax toxin-mediated delivery of a cytotoxic T-cell epitope in vivo. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12531-4.
Score: 0.109
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Coordination between T helper cells, iNKT cells, and their follicular helper subsets in the humoral immune response against Clostridium difficile toxin B. J Leukoc Biol. 2017 02; 101(2):567-576.
Score: 0.108
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Memory B Cells Encode Neutralizing Antibody Specific for Toxin B from the Clostridium difficile Strains VPI 10463 and NAP1/BI/027 but with Superior Neutralization of VPI 10463 Toxin B. Infect Immun. 2016 01; 84(1):194-204.
Score: 0.102
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Immunization of Mice with Anthrax Protective Antigen Limits Cardiotoxicity but Not Hepatotoxicity Following Lethal Toxin Challenge. Toxins (Basel). 2015 Jun 25; 7(7):2371-84.
Score: 0.099
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The primary structure of Clostridium septicum alpha-toxin exhibits similarity with that of Aeromonas hydrophila aerolysin. Infect Immun. 1995 Jan; 63(1):340-4.
Score: 0.096
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Activation and mechanism of Clostridium septicum alpha toxin. Mol Microbiol. 1993 Nov; 10(3):627-34.
Score: 0.089
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Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem. 2013 Jul 26; 288(30):21526-36.
Score: 0.086
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Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Infect Immun. 2012 Dec; 80(12):4374-87.
Score: 0.082
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Purification and characterization of the lethal toxin (alpha-toxin) of Clostridium septicum. Infect Immun. 1992 Mar; 60(3):784-90.
Score: 0.079
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Serum amyloid A protects murine macrophages from lethal toxin-mediated death. Cell Immunol. 2012; 272(2):175-81.
Score: 0.077
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Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFN?. PLoS One. 2011; 6(8):e23817.
Score: 0.076
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Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity. Vaccine. 2011 May 09; 29(20):3670-8.
Score: 0.074
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CD1d-dependent B-cell help by NK-like T cells leads to enhanced and sustained production of Bacillus anthracis lethal toxin-neutralizing antibodies. Infect Immun. 2010 Apr; 78(4):1610-7.
Score: 0.068
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Clostridium sordellii toxic shock syndrome. Lancet Infect Dis. 2009 Dec; 9(12):725-6.
Score: 0.068
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Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin. J Immunol. 2009 Nov 01; 183(9):5799-806.
Score: 0.067
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Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy. PLoS Pathog. 2009 Sep; 5(9):e1000588.
Score: 0.067
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The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes. Infect Immun. 2009 Nov; 77(11):4714-23.
Score: 0.066
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Sequential B-cell epitopes of Bacillus anthracis lethal factor bind lethal toxin-neutralizing antibodies. Infect Immun. 2009 Jan; 77(1):162-9.
Score: 0.063
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Bacillus anthracis oedema toxin as a cause of tissue necrosis and cell type-specific cytotoxicity. Cell Microbiol. 2005 Aug; 7(8):1139-49.
Score: 0.050
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Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):13803-8.
Score: 0.044
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The Murine Neonatal Fc Receptor Is Required for Transport of Immunization-Induced C. difficile-Specific IgG to the Gut and Protection against Disease but Does Not Affect Disease Susceptibility. Infect Immun. 2021 09 16; 89(10):e0027421.
Score: 0.038
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Clostridioides difficile Infection Induces an Inferior IgG Response to That Induced by Immunization and Is Associated with a Lack of T Follicular Helper Cell and Memory B Cell Expansion. Infect Immun. 2020 02 20; 88(3).
Score: 0.034
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Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity. Infect Immun. 1999 Jul; 67(7):3290-6.
Score: 0.033
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Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11. Mol Microbiol. 1998 Jul; 29(2):581-91.
Score: 0.031
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Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge. J Infect Dis. 2010 Jul 15; 202(2):251-60.
Score: 0.018