Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins.

Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins. J Biol Chem. 2012 Jul 13; 287(29):24534-43.

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subject areas

Cells, Cultured
Cells, Cultured
Cholesterol
Cholesterol
Electrophoresis, Polyacrylamide Gel
Electrophoresis, Polyacrylamide Gel
Fluorescence Resonance Energy Transfer
Fluorescence Resonance Energy Transfer
Hemolysis
Hemolysis
Humans
Humans
Microscopy, Electron
Microscopy, Electron
Perforin
Perforin
Point Mutation
Point Mutation
Protein Structure, Secondary
Protein Structure, Secondary
Protein Structure, Tertiary
Protein Structure, Tertiary

authors with profiles

Rodney Kim Tweten