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Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.
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Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.
Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. FASEB J. 2010 Apr; 24(4):1178-91.
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PubMed
subject areas
Animals
Animals
Disease Models, Animal
Disease Models, Animal
DNA
DNA
Genetic Therapy
Genetic Therapy
Humans
Humans
Interleukin-6
Interleukin-6
Intermediate Filament Proteins
Intermediate Filament Proteins
Macrophage Activation
Macrophage Activation
Macrophages
Macrophages
Membrane Glycoproteins
Membrane Glycoproteins
Mice
Mice
Mitosis
Mitosis
Mutation
Mutation
Nanoparticles
Nanoparticles
Nerve Tissue Proteins
Nerve Tissue Proteins
Opsins
Opsins
Peripherins
Peripherins
Promoter Regions, Genetic
Promoter Regions, Genetic
Retinal Cone Photoreceptor Cells
Retinal Cone Photoreceptor Cells
Retinal Rod Photoreceptor Cells
Retinal Rod Photoreceptor Cells
Retinitis Pigmentosa
Retinitis Pigmentosa
Time Factors
Time Factors
Transduction, Genetic
Transduction, Genetic
Tumor Necrosis Factor-alpha
Tumor Necrosis Factor-alpha
authors with profiles
Shannon M Conley