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Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane.
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Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane.
Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane. J Biol Chem. 2004 Jul 02; 279(27):28266-75.
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subject areas
Animals
Animals
Apoptosis Regulatory Proteins
Apoptosis Regulatory Proteins
Biotinylation
Biotinylation
Blotting, Western
Blotting, Western
Carrier Proteins
Carrier Proteins
Cell Death
Cell Death
Cell Line, Tumor
Cell Line, Tumor
Cell Membrane
Cell Membrane
Cells, Cultured
Cells, Cultured
Choline
Choline
Cholinergic Agents
Cholinergic Agents
DNA, Complementary
DNA, Complementary
Dose-Response Relationship, Drug
Dose-Response Relationship, Drug
Hemicholinium 3
Hemicholinium 3
Hippocampus
Hippocampus
Humans
Humans
Immunohistochemistry
Immunohistochemistry
Intracellular Signaling Peptides and Proteins
Intracellular Signaling Peptides and Proteins
Kinetics
Kinetics
Membrane Transport Proteins
Membrane Transport Proteins
Mice
Mice
Microscopy, Confocal
Microscopy, Confocal
Neuroblastoma
Neuroblastoma
Neurons
Neurons
Phenotype
Phenotype
Precipitin Tests
Precipitin Tests
Prosencephalon
Prosencephalon
Protein Binding
Protein Binding
Protein Structure, Tertiary
Protein Structure, Tertiary
Transfection
Transfection
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Qing Guo