"Tegafur" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.
| Descriptor ID |
D005641
|
| MeSH Number(s) |
D03.383.742.698.875.404.850
|
| Concept/Terms |
Tegafur- Tegafur
- 1-(Tetrahydro-2-furanyl)-5-fluorouracil
- N1-(2'-Tetrahydrofuryl)-5-fluorouracil
- 1-(2-Tetrahydrofuryl)-5-fluorouracil
- 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
|
Below are MeSH descriptors whose meaning is more general than "Tegafur".
Below are MeSH descriptors whose meaning is more specific than "Tegafur".
This graph shows the total number of publications written about "Tegafur" by people in this website by year, and whether "Tegafur" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tegafur" by people in Profiles.
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[Simultaneous detection of both non-Hodgkin's lymphoma cells and breast cancer cells in pleural effusion--a case report]. Gan To Kagaku Ryoho. 2003 Oct; 30(10):1523-7.
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Thymidylate synthetase and thymidine kinase activities in DMH-induced colon carcinomas in rats and effects of UFT. Bull Tokyo Med Dent Univ. 1986 Dec; 33(4):137-44.
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[Maximum tolerated dose of tegafur in rats]. Gan To Kagaku Ryoho. 1984 Oct; 11(10):2148-54.
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Stereoselective metabolism of ftorafur (R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil). Cancer Chemother Pharmacol. 1981; 7(1):55-9.
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Activation of Ftorafue [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil] to 5-fluorouracil and gamma-butyrolactone. Cancer Res. 1980 Aug; 40(8 Pt 1):2814-9.
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5-Fluorouracil concentrations in human plasma following R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) administration. Cancer Res. 1979 Oct; 39(10):4289-90.