"Interleukin-33" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A member of the INTERLEUKIN-1 protein  family involved in the maturation of TH2 CELLS and the activation of MAST CELLS; BASOPHILS; EOSINOPHILS and NK CELLS. It is also produced by ENDOTHELIAL CELLS; EPITHELIAL CELLS and FIBROBLASTS; where it can function as an alarmin to modulate immune and inflammatory responses to tissue damage.
    
			
			
				
				
					
						| Descriptor ID | D000067596 | 
					
						| MeSH Number(s) | D12.644.276.374.465.850 D12.776.467.374.465.850 D23.529.374.465.850 | 
					
						| Concept/Terms |  | 
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "Interleukin-33".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Interleukin-33".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Interleukin-33" by people in this website by year, and whether "Interleukin-33" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2018 | 1 | 0 | 1 | 
| 2019 | 0 | 1 | 1 | 
| 2021 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Interleukin-33" by people in Profiles.
						
					
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								Glucocorticoids and Androgens Protect From Gastric Metaplasia by Suppressing Group 2 Innate Lymphoid Cell Activation. Gastroenterology. 2021 08; 161(2):637-652.e4. 
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								Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3?-mediated restriction of epithelial IL-33. Nat Commun. 2021 02 05; 12(1):836. 
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								Anti-inflammatory mediators ST2 and SIGIRR are induced by diphenyldifluoroketone EF24 in lipopolysaccharide-stimulated dendritic cells. Immunobiology. 2020 03; 225(2):151886. 
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								Chitin promotes antigen-specific Th2 cell-mediated murine asthma through induction of IL-33-mediated IL-1? production by DCs. Sci Rep. 2018 08 06; 8(1):11721.