3-Phosphoinositide-Dependent Protein Kinases
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"3-Phosphoinositide-Dependent Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3).
    
			
			
				
				
					
						| Descriptor ID | D064413 | 
					
						| MeSH Number(s) | D08.811.913.696.620.682.700.745 | 
					
						| Concept/Terms | 3-Phosphoinositide-Dependent Protein Kinases3-Phosphoinositide-Dependent Protein Kinases3 Phosphoinositide Dependent Protein KinasesKinases, 3-Phosphoinositide-Dependent ProteinProtein Kinases, 3-Phosphoinositide-Dependent3-Phosphoinositide-Dependent Protein Kinase3 Phosphoinositide Dependent Protein KinaseKinase, 3-Phosphoinositide-Dependent ProteinProtein Kinase, 3-Phosphoinositide-Dependent
 3-Phosphoinositide Dependent Protein Kinase-13-Phosphoinositide Dependent Protein Kinase-13 Phosphoinositide Dependent Protein Kinase 13-Phosphoinositide-Dependent Protein Kinase-1Kinase-1, 3-Phosphoinositide-Dependent ProteinProtein Kinase-1, 3-Phosphoinositide-DependentPtdIns(3,4,5)P3-Dependent Protein Kinase-13-Phosphoinositide-Dependent Kinase 1 (PDK1)
 3-Phosphoinositide Dependent Protein Kinase-23-Phosphoinositide Dependent Protein Kinase-23 Phosphoinositide Dependent Protein Kinase 23-Phosphoinositide-Dependent Protein Kinase-2Kinase-2, 3-Phosphoinositide-Dependent ProteinProtein Kinase-2, 3-Phosphoinositide-Dependent
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				Below are MeSH descriptors whose meaning is more general than "3-Phosphoinositide-Dependent Protein Kinases".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "3-Phosphoinositide-Dependent Protein Kinases".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "3-Phosphoinositide-Dependent Protein Kinases" by people in this website by year, and whether "3-Phosphoinositide-Dependent Protein Kinases" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1997 | 0 | 1 | 1 | 
| 1999 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "3-Phosphoinositide-Dependent Protein Kinases" by people in Profiles.
						
					
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								PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2. Curr Biol. 1999 Apr 22; 9(8):393-404. 
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								3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr Biol. 1997 Oct 01; 7(10):776-89.