Quantitative Structure-Activity Relationship
"Quantitative Structure-Activity Relationship" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A quantitative prediction of the biological, ecotoxicological or pharmaceutical activity of a molecule. It is based upon structure and activity information gathered from a series of similar compounds.
| Descriptor ID |
D021281
|
| MeSH Number(s) |
G02.111.830.500 G07.690.773.997.500
|
| Concept/Terms |
Quantitative Structure-Activity Relationship- Quantitative Structure-Activity Relationship
- Quantitative Structure Activity Relationship
- Quantitative Structure-Activity Relationships
- Relationship, Quantitative Structure-Activity
- Relationships, Quantitative Structure-Activity
- Structure-Activity Relationship, Quantitative
- Structure-Activity Relationships, Quantitative
- Structure Activity Relationship, Quantitative
- QSAR
|
Below are MeSH descriptors whose meaning is more general than "Quantitative Structure-Activity Relationship".
Below are MeSH descriptors whose meaning is more specific than "Quantitative Structure-Activity Relationship".
This graph shows the total number of publications written about "Quantitative Structure-Activity Relationship" by people in this website by year, and whether "Quantitative Structure-Activity Relationship" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Quantitative Structure-Activity Relationship" by people in Profiles.
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Computer-Aided Design and Biological Evaluation of Diazaspirocyclic D4R Antagonists. ACS Chem Neurosci. 2024 Jun 19; 15(12):2396-2407.
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QSAR and deep learning model for virtual screening of potential inhibitors against Inosine 5' Monophosphate dehydrogenase (IMPDH) of Cryptosporidium parvum. J Mol Graph Model. 2022 03; 111:108108.
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An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive Probe. Free Radic Res. 2011 Feb; 45(2):237-47.
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Resisting degradation by human elastase: commonality of design features shared by 'canonical' plant and bacterial macrocyclic protease inhibitor scaffolds. Bioorg Med Chem. 2007 Jul 01; 15(13):4618-28.
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New approach to pharmacophore mapping and QSAR analysis using inductive logic programming. Application to thermolysin inhibitors and glycogen phosphorylase B inhibitors. J Med Chem. 2002 Jan 17; 45(2):399-409.