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Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.
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Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE.
Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE. Clin Immunol. 2016 08; 169:58-68.
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subject areas
ADAM10 Protein
ADAM10 Protein
ADAM17 Protein
ADAM17 Protein
Adult
Adult
Animals
Animals
Blotting, Western
Blotting, Western
Cell Line
Cell Line
Female
Female
Gene Expression
Gene Expression
Humans
Humans
Intercellular Signaling Peptides and Proteins
Intercellular Signaling Peptides and Proteins
Leukocytes, Mononuclear
Leukocytes, Mononuclear
Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
Macrophages
Macrophages
Male
Male
Mice, Inbred C57BL
Mice, Inbred C57BL
Mice, Inbred MRL lpr
Mice, Inbred MRL lpr
Mice, Knockout
Mice, Knockout
Middle Aged
Middle Aged
Proto-Oncogene Proteins
Proto-Oncogene Proteins
Receptor Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Reverse Transcriptase Polymerase Chain Reaction
Reverse Transcriptase Polymerase Chain Reaction
Young Adult
Young Adult
authors with profiles
Cristina Arriens